In the second half of the 19th century, Paris became an international center for neurological studies largely because of Jean-Martin Charcot and his Salpetriere School. Charcot was named Professor of Diseases of the Nervous System at the University of Paris in 1882, and thus helped institutionalize neurology as a medical specialty. By then he had already published widely and had assembled a team of research specialists and students who approached the study of the nervous system through the celebrated methode anatomo-clinique that correlated specific neurological signs with discrete lesions in the central nervous system. Pushing beyond the bounds of anatomical study, Charcot went on to study hysteria, attracting both scientific and social notoriety.
This book provides the best account of the life and contributions of Jean-Martin Charcot. It gives a fascinating picture of the man and his milieu, and clearly defines his role in establishing the new medical specialty of clinical neurology.

Placebo Effects in Neurologic Disease, Volume 153, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Background and Methods in Placebo, Better than Nothing: A Historical Account of Placebos and Placebo Effects from Modern to Contemporary Medicine, Determinants of PE, Strategies for Minimizing PE in Research, Maximizing placebo response in the clinic, Statistical methods for handling PE, Nocebo and Lessebo effects, Ethics of deception, Pain, Parkinson's Disease, Cognitive impairment, Epilepsy, and much more.

For many years, the need to develop valid tools to evaluate signs and symptoms of Parkinson Disease (PD) has been present. However the understanding of all intricacies of rating scales development was not widely available and the first attempts were relatively crude. In 2002, the Movement Disorders Society created a task force to systemize the measurement of Parkinson's Disease. Since then, the Task Force has produced and published several critiques to the available rating scales addressing both motor and non-motor domains of Parkinson Disease. Additionally the task force initiated a project to develop a new version of the UPDRS, the MDS-UPDRS. But none of this was made available in one convenient source. Until now.
Rating Scales in Parkinson's Disease: Clinical Practice and Research is written for researchers from the medical and social sciences, and for health professionals wishing to evaluate the progress of their patients suffering from Parkinson's Disease. The book is both exhaustive in the description of the scales and informative on the advantages and limitations of each scale. As such, the text clearly guides readers on how to choose and use the instruments available. Extensive cross-referenced tables and charts closely integrate the parts of the book to facilitate readers in moving from one symptom domain to another.