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Despite being regarded as the most common toxicological target in
the endocrine system, the adrenal gland has often been neglected in
regulatory testing. Adrenal Toxicology addresses the increased
interest in adrenocortical toxicology and the need for a resource
that makes techniques available to examine adrenal endocrine
disruption. Examining current techniques and the latest
advancements, Adrenal Toxicology reviews the endocrinology,
pharmacology, pathology and toxicology of the adrenal gland. This
text provides information on the range of drugs and chemicals that
affect adrenocortical function and suggests standardized approaches
for in vivo and in vitro assessment. This volume also presents
recent developments in the molecular mechanisms of toxicity to the
adrenal cortex and medulla, and considers environmental adrenal
endocrine disruption in sentinel species. Adrenal Toxicology:
reflects the major developments made over the past decade focuses
on the latest research techniques, including their uses and
limitations provides an integrated strategy for adrenal toxicology
evaluation identifies knowledge and data gaps, providing impetus
for regulatory consideration
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