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This collection of diverse articles by the pioneers of modern
genomics takes stock of the current state of the field and
elucidates the contribution that sequencing genomes has made to our
understanding of microbial metabolism and evolution. Through
twenty-eight thought-provoking chapters, the authors describe some
of the most common computational methods and their applications to
studying pathogenic microorganisms, show how genomics can be used
to reconstruct the history and dynamism of the microbial world, and
discuss issues as diverse as reconstruction of metabolic pathways,
cell cycle processes, microbial evolution, metagenomics, and
vaccine development. Additional chapters deal with microarrays and
expression analysis and the role of genomic in drug discovery.
This collection of diverse articles by the pioneers of modern
genomics takes stock of the current state of the field and
elucidates the contribution that sequencing genomes has made to our
understanding of microbial metabolism and evolution. Through
twenty-eight thought-provoking chapters, the authors describe some
of the most common computational methods and their applications to
studying pathogenic microorganisms, show how genomics can be used
to reconstruct the history and dynamism of the microbial world, and
discuss issues as diverse as reconstruction of metabolic pathways,
cell cycle processes, microbial evolution, metagenomics, and
vaccine development. Additional chapters deal with microarrays and
expression analysis and the role of genomic in drug discovery.
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