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Conceptual advances in the biological sciences are marked by the
applica tion of new techniques and experimental strategies. Nowhere
has this ge neric principle been more apparent than in the study of
testicular cells, as judged by the evolution of themes presented at
the Testis Workshop over the past 23 years. Like its predecessors,
the 1995 Testis Workshop was structured to offer fresh insights and
approaches for understanding the mechanisms of spermatogenesis and
steroidogenesis. The chapters pre sented in this book emphasize
three aspects of testicular cell function: first, the molecular
analysis of the cell cycle; second, examination of the cell cycle,
including the function and identification of specific
macromolecules that direct the proliferation and differentiation of
germ cells; and third, the development of Leydig cells and the role
of specific macromolecules in the formation of testicular steroids.
Each chapter is based on a lecture presented at the XIIIth Testis
Work shop held on March 30 to April 1, 1995, at the Radisson Plaza
Hotel in Raleigh, North Carolina. The selection of topics reflects
the recommenda tions of the workshop'S organizing committee.
Sincere thanks are due to the speakers who agreed to lecture and
prepare chapters."
This book is a comprehensive, multi-authored work on the structure
and function of the mammalian testis. The approach emphasizes gene
expression, translation and production of specific gene products
and the cellular and molecular regulation of these fundamental
processes. Rather than provide a global survey of all aspects of
male reproduction, this book stresses specific mechanisms that
underscore the structure and function of the testis. It explains
old and new concepts from a cellular and molecular perspective.
This novel approach allows the authors to forge links between cell
and molecular biology and well-established aspects of
spermatogenesis and steroidogenesis. The result is a well-focused,
comprehensive, and synthetic analysis of testicular biology.
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