All episodes from the television drama series following Dr. Eleanor Bramwell (Jemma Redgrave) as she treats patients in a male-dominated profession in Victoria London. She is ridiculed by the other doctors because she is female and even her father (David Calder), who is also a doctor, questions her. She gets a chance to have a more influential position in the medical world when Lady Peters (Michele Dotrice) gives her a renovated building which Eleanor turns into a free hospital, where the poor citizens of the East End are able to seek help. Can she continue to strive in such a difficult profession, in an era when women were thought to belong in the home?

In 1714 Parliament offer a £20,000 prize for anyone who can provide an accurate means of measuring longitude at sea. John Harrison (Michael Gambon) flies in the face of popular opinion by saying that the stars do not provide the answer, and provides his own solution with the invention of a mechanical clock. However, it takes Harrison forty years to prove his theory, and he is eventually forgotten in the mists of time. Centuries later, Robert Gould (Jeremy Irons) attempts to restore Harrison's reputation by tracking down and repairing the four clocks he originally constructed.