|
Showing 1 - 5 of
5 matches in All Departments
Translational Research is the interface between basic science and
human clinical application, including the entire process from
animal studies to human clinical trials (phases I, II, and III).
Translational Research moves promising basic science results from
the laboratory to bedside application. Yet, this transition is
often the least-defined, least-understood part of the research
process. Most scientific training programs provide little or no
systematic introduction to the issues, challenges, and obstacles
that prevent effective research translation, even though these are
the key steps that enable high-impact basic science to ultimately
result in significant clinical advances that improve patient
outcome. This volume will provide an overview of key issues in
translation of research from "bedside to bench to bedside", not
only from the perspective of the key funding agencies, but also
from the scientists and clinicians who are currently involved in
the translational research process. It will attempt to offer
insight into real-world experience with intellectual property and
technology transfer activities that can help move auditory
technologies ahead, as scientists and clinicians typically have
little or no formal training in these areas. Translational Research
in Audiology and the Hearing Sciences will be aimed at graduate
students and postdoctoral investigators, as well as professionals
and academics. It is intended to function as a high-profile and
up-to-date reference work on Translational Research in the auditory
sciences, emphasizing research programs in the traditional areas
including drugs and devices, as well as less traditional, still
emerging, areas such as sensorineural hearing loss, auditory
processing disorder, cochlear implants and hearing aids, and
tinnitus therapies.
Translational Research is the interface between basic science and
human clinical application, including the entire process from
animal studies to human clinical trials (phases I, II, and III).
Translational Research moves promising basic science results from
the laboratory to bedside application. Yet, this transition is
often the least-defined, least-understood part of the research
process. Most scientific training programs provide little or no
systematic introduction to the issues, challenges, and obstacles
that prevent effective research translation, even though these are
the key steps that enable high-impact basic science to ultimately
result in significant clinical advances that improve patient
outcome. This volume will provide an overview of key issues in
translation of research from "bedside to bench to bedside", not
only from the perspective of the key funding agencies, but also
from the scientists and clinicians who are currently involved in
the translational research process. It will attempt to offer
insight into real-world experience with intellectual property and
technology transfer activities that can help move auditory
technologies ahead, as scientists and clinicians typically have
little or no formal training in these areas. Translational Research
in Audiology and the Hearing Sciences will be aimed at graduate
students and postdoctoral investigators, as well as professionals
and academics. It is intended to function as a high-profile and
up-to-date reference work on Translational Research in the auditory
sciences, emphasizing research programs in the traditional areas
including drugs and devices, as well as less traditional, still
emerging, areas such as sensorineural hearing loss, auditory
processing disorder, cochlear implants and hearing aids, and
tinnitus therapies.
This comprehensive volume examines the current state of free
radical biology and its impact on otology, laryngology, and head
and neck function. The chapters collectively highlight the
interrelationship of basic and translational studies in each area,
define the challenges to translation, and identify the existing
basic issues that demand investigation as well as the opportunities
for novel intervention to prevent and treat ENT pathology and
impairment. In each chapter, or in some cases pairs of chapters,
the author(s) have included or married issues of basic research
with translational challenges and research, thus defining the
pathway by which new basic insights may lead to interventions to
prevent or treat impairment. The final chapter of this book
reflects a meeting of all the contributors, culminating in a
discussion and "white paper" that identifies the challenges to the
field and defines the studies and collaborations that may lead to
improved understanding of free radical biology in ENT and,
subsequently, new interventions to medically treat ENT pathology.
Exposure to loud noise continues to be the largest cause of hearing
loss in the adult population. The problem of NIHL impacts a number
of disciplines. US standards for permissible noise exposure were
originally published in 1968 and remain largely unchanged today.
Indeed, permissible noise exposure for US personnel is
significantly greater than that allowed in numerous other
countries, including for example, Canada, China, Brazil, Mexico,
and the European Union. However, there have been a number of
discoveries and advances that have increased our understanding of
the mechanisms of NIHL. These advances have the potential to impact
how NIHL can be prevented and how our noise standards can be made
more appropriate.
Exposure to loud noise continues to be the largest cause of hearing
loss in the adult population. The problem of NIHL impacts a number
of disciplines. US standards for permissible noise exposure were
originally published in 1968 and remain largely unchanged today.
Indeed, permissible noise exposure for US personnel is
significantly greater than that allowed in numerous other
countries, including for example, Canada, China, Brazil, Mexico,
and the European Union. However, there have been a number of
discoveries and advances that have increased our understanding of
the mechanisms of NIHL. These advances have the potential to impact
how NIHL can be prevented and how our noise standards can be made
more appropriate.
|
You may like...
Merry Christmas
Mariah Carey, Walter Afanasieff, …
CD
R122
R112
Discovery Miles 1 120
|