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A medical book need not be pretty, but it must be necessary and
informative. This monograph on the clinical and diagnostic
pathology of graft-versus-host disease, provid ing detailed visual
information on the histo morphological and immunohistological fea
tures of GvHD, is intended to close a gap in the otherwise
comprehensive medical literature on GvHD. B. Heymer
Acknowledgements No one accumulates knowledge alone. lowe thanks
to: Prof. G. R. F. Kruger, Houston, for introducing me to the
histomorphological analysis of GvHD Prof. R. Arnold, Berlin, for
many fruitful clinico pathological discussions Prof. K. H.
Muller-Hermelink, Wurzburg, for expert advice in difficult
histological differential diagnoses Prof. W. Mohr, Ulm, for
continuous support and encouragement in moments of fatigue Last,
but by no means least, Mrs. R. Endres-Klein, Ulm, without whom the
preparation of this book would have been impossible In addition, I
am grateful to the editorial staff at Springer, Heidelberg. B.
Heymer Contents 1 Introduction. . . . . . . . . . . . . 1 1. 1 What
Is Graft-Versus-Host Disease? 1 1. 2 Has the Pathology of GvHD
Changed in the Past Decades? . . . . 1 1. 3 Why Write a Synopsis of
the Clinical and Diagnostic Pathology of GvHO? 2 2 Occurrence of
GvHD . . . . . . . . . 5 2. 1 GvHD After Allogeneic Bone Marrow
Transplantation . . . . . . . . . . . . . 6 2. 2 GvHD After
Allogeneic Peripheral Blood Stem Cell Transplantation 6 2. 3
Alternative Donors . . . . . . . . . . . . 7 2. 4 Umbilical Cord
Blood . . . . . . . . . . 7 2. 5 GvHD After Materno-fetal
Transfusion 8 2. 6 GvHD After Blood Transfusion . . . . . 9 2."
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