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The goal of this book series has been to provide an overview of
rhabdovirology as a whole (including an appraisal of current
research findings), suitable for students, teachers, and, research
workers. To realize this goal many of the research leaders in the
different disciplines of rhabdovirology were asked to contribute
chapters.
The control of cancer is at once a major public health problem and
a problem of fundamental biologic interest. As a result of
technologic developments and new insights in the realm of molecular
biology, new and important approaches to an understanding of
neoplasia are now possible. Several aspects of neoplasia are
clearly of microbiologic interest, including the role of viruses in
the etiology of cancer, control of the immune response to tumor
cells, and the susceptibility of tumor-bearing hosts to
overwhelming infection as a result of immuno deficiency. Recent
advances in these areas led us to organize this symposium, and,
through this publication, to record some of the progress being made
in laboratories around the world in understanding some of the basic
aspects of the cancer problem. This symposium was held as part of
the commemoration of the twentieth anniversary of the Waksman
Institute of Microbiology. Dr. Waksman's devo tion to the study of
the smallest forms of life and the commitment of the Waksman
Institute to the free pursuit of knowledge are the underpinnings of
the institute's research eHorts in the broad area of microbiology,
including the problem of neoplasia. It is of interest to note that
actinomycin, one of the earliest antibiotics discovered in
Waksman's laboratory, was also one of the first compounds found to
be clinically useful in the treatment of certain types of cancer."
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