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This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.
This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract. The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.
Axel Honneth is one of the most influential social and political philosophers in contemporary German political thought and one of the central figures of the third generation of the Frankfurt School. Honneth's philosophical project presents at once a solution to a problem that has beset Frankfurt School Critical Theory from the first generation onwards, and offers a re-conceptualisation of social philosophy and its methodology in general. Honneth's work presents a viable alternative to mainstream (especially Rawlsian) political philosophy by taking on challenges mainstream theories tend to avoid. This book provides one of the first substantial critical assessments of Honneth's achievements so far. Dagmar Wilhelm locates Honneth in critical theory and mainstream political theory debates and offers a detailed exploration of his account of social philosophy, methodology, social pathology, recognition, and humiliation. The book also includes an in-depth discussion of Honneth's critique of capitalism and programme for the new left and an assessment of the future of the project of the Frankfurt School in light of Honneth's approach.
Axel Honneth is one of the most influential social and political philosophers in contemporary German political thought and one of the central figures of the third generation of the Frankfurt School. Honneth's philosophical project presents at once a solution to a problem that has beset Frankfurt School Critical Theory from the first generation onwards, and offers a re-conceptualisation of social philosophy and its methodology in general. Honneth's work presents a viable alternative to mainstream (especially Rawlsian) political philosophy by taking on challenges mainstream theories tend to avoid. This book provides one of the first substantial critical assessments of Honneth's achievements so far. Dagmar Wilhelm locates Honneth in critical theory and mainstream political theory debates and offers a detailed exploration of his account of social philosophy, methodology, social pathology, recognition, and humiliation. The book also includes an in-depth discussion of Honneth's critique of capitalism and programme for the new left and an assessment of the future of the project of the Frankfurt School in light of Honneth's approach.
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