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This volume details state-of-the- art methods on computer-aided
antibody design. Chapters guide readers through information on
antibody sequences and structures, modeling antibody structures and
dynamics, prediction and optimization of biological and biophysical
properties of antibodies, prediction of antibody-antigen
interactions, and computer-aided antibody affinity maturation and
beyond. Written in the format of the highly successful Methods in
Molecular Biology series, each chapter includes an introduction to
the topic, lists necessary materials and reagents, includes tips on
troubleshooting and known pitfalls, and step-by-step, readily
reproducible protocols. Authoritative and cutting-edge,
Computer-Aided Antibody Design aims to be a useful and practical
guide to new researchers and experts looking to expand their
knowledge. Chapter 2 is available open access under a Creative
Commons Attribution 4.0 International License via
link.springer.com.
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