Focused extensively on the toxic effect of chemicals on the cardiovascular system, Cardiovascular Toxicology, Fourth Edition is comprised of several key sections beyond cardio and vascular toxicity, such as principles of myocardial cell injury and key methods of assessing cardiovascular function. New developments include: expanded chapter on passive smoking, which includes adverse effects of smoking, and the effects of secondary smoke new chapter on the negative effects from environmental chemicals on the cardiovascular system chapters covering antibacterial agents and endotoxins include new information on cardiovascular toxicity of antimicrobials, as well as anti-viral agents, antibacterial agents, and other agents

2019 Paterson Prize winner Skipping Stones Book Award Kirkus Reviews' Best YA Historical Fiction of 2018 A river runs through young Manny Maldonado Jr.'s life, heart and imagination. Sometimes at night it even shoots through his brain like a bullet. But this river isn't water, it's iron-the tracks and trains of the Southern Pacific railroad that pass along his tight-knit neighborhood in the San Gabriel valley just ten miles east of L.A. The iron river is everything to Man-on-Fire, Man for short to his friends, Little Man to his uncles and cousins. He watches it, he waits for it, he plays nears its tracks, he listens for the weight of its currents (strong currents flowing east pulling two hundred boxcars, light current going west with less than fifty cars), he whiles away long summer days throwing rocks and bricks at it with his friends Danny, Marco and Little. They line up cans and bottles in mock battles to try to throw it off track. But nothing derails the iron river, and nothing stops the stinking cop Turk from trying to pin a hobo's murder on the four young boys.