Recent developments in lesion-symptom mapping (LSM) have spurred rapid growth. This volume provides comprehensive coverage of the steps and considerations involved in LSM. The chapters cover the definition and types of brain lesions, how to prepare them for analysis, standard LSM methods, network-based LSM methods, and approaches of transient lesions induced by brain stimulation. These chapters are supplemented by practical, hands-on mini tutorials on implementing the different analyses using freely-available software. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get started using LSM in your laboratory. Cutting-edge and thorough, Lesion-to-Symptom Mapping: Principles and Tools connects core conceptual issues with available tools, making it a valuable resource for experienced and new researchers.

Learn How to Use Growth Curve Analysis with Your Time Course Data An increasingly prominent statistical tool in the behavioral sciences, multilevel regression offers a statistical framework for analyzing longitudinal or time course data. It also provides a way to quantify and analyze individual differences, such as developmental and neuropsychological, in the context of a model of the overall group effects. To harness the practical aspects of this useful tool, behavioral science researchers need a concise, accessible resource that explains how to implement these analysis methods. Growth Curve Analysis and Visualization Using R provides a practical, easy-to-understand guide to carrying out multilevel regression/growth curve analysis (GCA) of time course or longitudinal data in the behavioral sciences, particularly cognitive science, cognitive neuroscience, and psychology. With a minimum of statistical theory and technical jargon, the author focuses on the concrete issue of applying GCA to behavioral science data and individual differences. The book begins with discussing problems encountered when analyzing time course data, how to visualize time course data using the ggplot2 package, and how to format data for GCA and plotting. It then presents a conceptual overview of GCA and the core analysis syntax using the lme4 package and demonstrates how to plot model fits. The book describes how to deal with change over time that is not linear, how to structure random effects, how GCA and regression use categorical predictors, and how to conduct multiple simultaneous comparisons among different levels of a factor. It also compares the advantages and disadvantages of approaches to implementing logistic and quasi-logistic GCA and discusses how to use GCA to analyze individual differences as both fixed and random effects. The final chapter presents the code for all of the key examples along with samples demonstrating how to report GCA results. Throughout the book, R code illustrates how to implement the analyses and generate the graphs. Each chapter ends with exercises to test your understanding. The example datasets, code for solutions to the exercises, and supplemental code and examples are available on the author's website.

Recent developments in lesion-symptom mapping (LSM) have spurred rapid growth. This volume provides comprehensive coverage of the steps and considerations involved in LSM. The chapters cover the definition and types of brain lesions, how to prepare them for analysis, standard LSM methods, network-based LSM methods, and approaches of transient lesions induced by brain stimulation. These chapters are supplemented by practical, hands-on mini tutorials on implementing the different analyses using freely-available software. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get started using LSM in your laboratory.  Cutting-edge and thorough, Lesion-to-Symptom Mapping: Principles and Tools connects core conceptual issues with available tools, making it a valuable resource for experienced and new researchers.