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This book contains 14 original review chapters each yielding new,
exciting and intriguing data about the emerging understanding of
nucleolar structure and function in normal, stressed and diseased
cells. The goal of this work is to provide special insight into the
nucleolus of the past, present and future, as well its regulation,
translocation, and biomedical function. A multitude of topics are
introduced and discussed in detail, including nucleologenesis,
nucleolar architecture, nucleolar targeting, retention, anchoring,
translocation, and the relationship between the nucleolus and
cancer. This book also brings together work from several different
species, from human to Drosophila to Dictyostelium and other
eukaryotic microbes. The final chapter summarizes some of the
issues brought up in the various chapters with a view to future
research. This book supports the continued emergence of the
nucleolus as a dynamic intranuclear region that oversees a vast
diversity of events.
This book contains 14 original review chapters each yielding new,
exciting and intriguing data about the emerging understanding of
nucleolar structure and function in normal, stressed and diseased
cells. The goal of this work is to provide special insight into the
nucleolus of the past, present and future, as well its regulation,
translocation, and biomedical function. A multitude of topics are
introduced and discussed in detail, including nucleologenesis,
nucleolar architecture, nucleolar targeting, retention, anchoring,
translocation, and the relationship between the nucleolus and
cancer. This book also brings together work from several different
species, from human to Drosophila to Dictyostelium and other
eukaryotic microbes. The final chapter summarizes some of the
issues brought up in the various chapters with a view to future
research. This book supports the continued emergence of the
nucleolus as a dynamic intranuclear region that oversees a vast
diversity of events.
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