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The poems in Falling Body, David Cavanagh's second collection, cover ground with quirkiness. precision, and grace. They move the way a life moves-in and out of personal and public territory, past and present perspectives, inner and outer worlds. They chart inevitable falls and celebrate (sometimes with wry humor, sometimes with muted joy) getting up again. The poems touch down lightly on large topics and move on, nervous of becoming trapped in easy certainties. They love the complexities while yearning for simplicity.
Interest in the coronaviruses has never been greater. Their economic impact is considerable as they infect humans, livestock, poultry and companion animals. Murine hepatitis virus (MHV) infection of the mouse and rat central nervous systems are the subject of intense study; these investigations are providing insights into the potential role of viruses in human neurological diseases and, more generally, into mechanisms causing neurological damage. The single-stranded, positive-sense RNA genomes of two species of these enveloped viruses (IBV and MHV) have been cloned completely and one of them (lBV) sequenced in its entirety, revealing a genome size of some 27000 nucleotides. This has made possible more incisive investigations into the nature of those polypeptides, encoded by more than half of the genome, which are likely to contribute, in the main, to RNA polymerase/replicase activity. Intriguingly, ribosomal frameshifting is exhibited within the mRNA coding for these polypeptides. The cloning/sequencing phase of coronavirology for which the 1980's will be partly remembered, has provided a sound framework for furthex: studies of the virus structural proteins and also some provocative insights relevant to these studies. The large spike glycoprotein(s), responsible for membrane fusion and bearing important antigenic sites, varies amazingly in length and composition both within as well as between coronavirus species. Receptors on host cells have been identified. The integral membrane glycoprotein (M) has been shown to use internal hydrophobic sequences to direct translocation within membranes.
'The greatest book ever written on British independent music' Guardian 'One of the best British music books of the last ten years' Mojo Founded by Alan McGee in 1983, Creation Records achieved notoriety as the home of Primal Scream, the Jesus and Mary Chain and other anti-Establishment acts. During the Britpop boom of the mid-90s, the astonishing success of Oasis brought Creation fame on the world stage. In 1999, however, McGee announced his shock departure as his label's influence over a generation of British music came to a confusing and disappointing end. Containing interviews with Creation musicians, employees, supporters and detractors, this is the inside story of Creation Records - and of British music since the 1980s.
Goodnight and Good Riddance: How Thirty-Five Years of John Peel Helped to Shape Modern Britain is a social history, a diary of a nation's changing culture, and an in-depth appraisal of one of our greatest broadcasters, a man who can legitimately be called the most influential figure in post-war British popular music. Without the support of John Peel, it's unlikely that innumerable artists - from David Bowie to Dizzee Rascal, Jethro Tull to Joy Division - would have received national radio exposure. But Peel's influence goes much deeper than this. Whether he was championing punk, reggae, jungle or grime, he had a unique relationship with his audience that was part taste-maker, part trusted friend. The book focuses on some 300 shows between 1967 and 2004, giving a thorough overview of Peel's broadcasting career and placing it in its cultural and social contexts. Peel comes alive for the reader, as do the key developments that kept him at the cutting edge - the changes in his tastes; the changes in his thinking. Just like a Peel show, Goodnight and Good Riddance is warm, informative and insightful, and wears its enthusiasm proudly.
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