This volume discusses methods used in the fields of molecular and cellular biology for detecting and studying cell death, especially in cancer and cancer therapy. Chapters in this book cover topics such as non-destructive, real-time Annexin V apoptosis assay; assessment of the immune response to tumor cell apoptosis and efferocytosis; mass cytometry assessment of cell phenotypes and signaling states in human whole blood; cell cycle analysis of ER stress and autophagy; and simultaneous detection of inflammasome activation and membrane damage during pyroptosis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Apoptosis and Cancer: Methods and Protocols is a valuable resource and practical guide for both novice and expert researchers looking into the "meaning of death."

Christmas is coming and Carlos and his family are going home-driving south across the border to Mexico. But Mexico doesn't seem like home to Carlos, even though he and his sisters were born there. Can home be a place you don't really remember?

At first, La Perla doesn't seem very different from the other villages they pass through. But then Carlos is swept into the festivities by Grandfather, Aunt Ana, and the whole village. Finally, Carlos begins to understand Mama and Papa's love for the place they left behind, and realizes that home can be anywhere, because it stays in the hearts of the people who love you.

Eve Bunting and David Diaz-the Caldecott Medal-winning team behind Smoky Night- collaborated once again to create a dazzling picture book that glows with holiday joy and the spirit of Mexico.

Tracker. The very word evokes images of buckskin-clad braves crouching over the ground, carefully studying the signs before them--a part of history. But the modern world has not put behind it the need for the earthy business of tracking. Such skills are still routinely used by the military, rescue personnel, and law enforcement, as well as by hunters and people living at subsistence level throughout the world. "Tracking Humans "is the ultimate authoritative guide to this most complex pursuit. A great resource for military, law enforcement, and rescue professionals, "Tracking Humans "is also useful for outdoor enthusiasts. Users will find it invaluable as an on-site manual to assist in any ongoing search.Unlike many tracking manuals, this guide focuses on tracking humans, whether they're enemy combatants or lost children. Author David Diaz explains what it takes to be an expert tracker, from the physical stamina to the focus and perception necessary to do the job correctly. He explains the tools of the tracker and presents essential safety tips every tracker should know. "Tracking Humans" is an important tool for anyone dealing with missing persons--it could be an essential lifesaver.

Examine alternative strategies to resolving important Latino social issues! Latino Social Policy: A Participatory Research Model examines the failure of traditional research methods to address major social needs in Latino communities, promoting instead a participatory/action approach to research that is sociallyand scientificallymeaningful. Experts from a variety of disciplines focus on nontraditional strategies that engage community residents in community-research projects, shortening the distance between the researcher and the subject. This unique book recounts lessons learned on conducting Participatory Action Research (PAR) in Latino communities using techniques based on anthropology, education, community health and evaluation, and urban planning. Latino Social Policy: A Participatory Research Model addresses non-traditional methods of reducing the tension between the reality of interaction with the subject community and the academic training structures used by researchers. The book promotes a new vision and practice of research design in which the subject is central to the process, advocating a participatory approach to produce qualitatively different research based on community identified problems and needs. Contributors examine the value of integrating local knowledge, language, and culture into the methodological design, the ethics of conducting research in Latino communities, and the internal conflicts Chicana/o researchers face within their profession and in the field. Topics addressed in Latino Social Policy: A Participatory Research Model include: community health and Central Americans in Los Angeles ethnography and substance abuse among transnational Mexican farmworkers identity and field research in Mexico the Latino Coalition for a New Los Angeles (LCNLA) researcher/community partnerships and much more! Latino Social Policy: A Participatory Research Model includes case studies, ethnographies, and vignettes that illustrate participatory approaches and outcomes in Latino research. The book is equally valuable as a textbook for academics and students working in the social sciences, public policy, and urban planning, and as a professional guide for community leaders and organizations interested in developing research partnerships.

Experiencing both the enormous benefits and the serious detriments of globalization and economic restructuring, Southern California serves as a magnet for immigrants from many parts of the world. This volume advances an emerging body of work that centers this region's future on the links between the two fastest-growing racial groups in California, Asians and Latinos, and the economic and social mainstream of this important sector of the global economy.
The contributors to the anthology--scholars and community leaders with social science, urban planning, and legal backgrounds--provide a multi-faceted analysis of gender, class, and race relations. They also examine various forms of immigrant economic participation, from low-wage workers to entrepreneurs and capital investors. "Asian and Latino Immigrants in a Restructuring Economy" documents the entrenchment of various immigrant communities in the socio-political and economic fabric of United States society and these communities' role in transforming the Los Angeles region.

In a night of rioting, Daniel and his mother are forced to leave their apartment for the safety of a shelter. "Diaz has not been afraid to take risks in illustrating the story with thickly textured paintings against a background of torn-paper and found-object collage. Without becoming cluttered or gimmicky, these pictures manage to capture a calamitous atmosphere that finally calms. . . . Both author and artist have managed to portray a politically charged event without pretense or preaching."--"The Bulletin"

"The sea, the sea, the sea. It rolled and rolled and called to me. Come in, it said, come in."

Thirteen-year-old Sophie hears the sea calling, promising adventure and a chance for discovery as she sets sail for England with her three uncles and two cousins. Sophie's cousin Cody isn't sure he has the strength to prove himself to the crew and to his father. Through Sophie's and Cody's travel logs, we hear stories of the past and the daily challenges of surviving at sea as The Wanderer sails toward its destination -- and its passengers search for their places in the world.

Using local materials and the primitive methods of the Casas Grandes people, Juan

Quezada creates stunning pots in the traditional style. Each is a work of art unlike any other.

This is the pot that Juan built.

These are the flames so sizzling hot

That flickered and flared and fired the pot,

The beautiful pot that Juan built.

Written in the form of "The House That Jack Built" and accompanied by explanatory material, this celebratory story is also the tale of the village of Mata Ortiz and its people. Juan's pioneering work has transformed Mata Ortiz from an impoverished village into a prosperous community of world-renowned artists.

With vibrant illustrations by Caldecott Medal winner David Diaz, The Pot That Juan Built is sure to enlighten all who are fascinated by traditional art forms, Mexican culture, and the power of the human spirit to find inspiration from the past.

Examine alternative strategies to resolving important Latino social issues! Latino Social Policy: A Participatory Research Model examines the failure of traditional research methods to address major social needs in Latino communities, promoting instead a participatory/action approach to research that is sociallyand scientificallymeaningful. Experts from a variety of disciplines focus on nontraditional strategies that engage community residents in community-research projects, shortening the distance between the researcher and the subject. This unique book recounts lessons learned on conducting Participatory Action Research (PAR) in Latino communities using techniques based on anthropology, education, community health and evaluation, and urban planning. Latino Social Policy: A Participatory Research Model addresses non-traditional methods of reducing the tension between the reality of interaction with the subject community and the academic training structures used by researchers. The book promotes a new vision and practice of research design in which the subject is central to the process, advocating a participatory approach to produce qualitatively different research based on community identified problems and needs. Contributors examine the value of integrating local knowledge, language, and culture into the methodological design, the ethics of conducting research in Latino communities, and the internal conflicts Chicana/o researchers face within their profession and in the field. Topics addressed in Latino Social Policy: A Participatory Research Model include: community health and Central Americans in Los Angeles ethnography and substance abuse among transnational Mexican farmworkers identity and field research in Mexico the Latino Coalition for a New Los Angeles (LCNLA) researcher/community partnerships and much more! Latino Social Policy: A Participatory Research Model includes case studies, ethnographies, and vignettes that illustrate participatory approaches and outcomes in Latino research. The book is equally valuable as a textbook for academics and students working in the social sciences, public policy, and urban planning, and as a professional guide for community leaders and organizations interested in developing research partnerships.

Opinions of specialized labor courts differ, but labor justice undoubtedly represented a decisive moment in worker 's history. When and how did these courts take shape? Why did their originators consider them necessary? Leon Fink and Juan Manuel Palacio present essays that address these essential questions. Ranging from Canada and the United States to Chile and Argentina, the authors search for common factors in the appearance of labor courts while recognizing the specific character of the creative process in each nation. Their transnational and comparative approach advances a global perspective on the various mechanisms for regulating industrial relations and resolving labor conflicts. The result is the first country-by-country study of its kind, one that addresses a defining shift in law in the first half of the twentieth century. Contributors: Rossana Barragan Romano, Angela de Castro Gomes, David Diaz-Arias, Leon Fink, Frank Luce, Diego Ortuzar, German Palacio, Juan Manuel Palacio, William Suarez-Potts, Fernando Teixeira da Silva, Victor Uribe-Uran, Angela Vergara, and Ronny J. Viales-Hurtado.

"Once upon a time in a cornfield there lived a scarecrow and his scarecrow wife and their little scarecrow boy." So begins Margaret Wise Brown's long lost treasure about a little scarecrow boy and the lessons he learns from his scarecrow father every day of the world, until the time he decides to test his knowledge and himself. Published here for the first time as a picture book, The Little Scarecrow Boy is a timeless story about the things children cherish family, home, and their place in the world. Tender and funny, it celebrates the tradition of passing knowledge from one generation to the next, and the exuberance that comes with reaching one's full potential. Known for his stunning design and breathtaking craftsmanship, Caldecott medal recipient, David Diaz declares an entirely new direction with The Little Scarecrow Boy. He perfectly captures the essence of this all-but-forgotten gem of a story with a bright palette and a remarkably fresh, childlike view of the world.

Experiencing both the enormous benefits and the serious detriments of globalization and economic restructuring, Southern California serves as a magnet for immigrants from many parts of the world. This volume advances an emerging body of work that centers this region's future on the links between the two fastest-growing racial groups in California, Asians and Latinos, and the economic and social mainstream of this important sector of the global economy.
The contributors to the anthology--scholars and community leaders with social science, urban planning, and legal backgrounds--provide a multi-faceted analysis of gender, class, and race relations. They also examine various forms of immigrant economic participation, from low-wage workers to entrepreneurs and capital investors. "Asian and Latino Immigrants in a Restructuring Economy" documents the entrenchment of various immigrant communities in the socio-political and economic fabric of United States society and these communities' role in transforming the Los Angeles region.

Thirteen young Latinos and Latinas living in America are introduced in this book celebrating the rich diversity of the Latino and Latina experience in the United States. Free-verse fiction and nonfiction prose present the characters' lives as well as important events in Latin American and Spanish history and culture.

On the heels of their Caldecott Medal-winning Smoky Night, Eve Bunting and David Diaz have created a dazzling new picture book that glows with holiday joy and the spirit of Mexico. Carlos and his family are going home for Christmas—across the border from California to Mexico. Mama and Papa are excited, but Carlos and his sisters are not so sure. To them, California is home now, even though they were born in Mexico. But as the family drives to their hometown through festive villages and sun-kissed landscapes, Carlos and his sisters discover there’s magic in their roots and that—whether in Mexico or California—home is where the heart is: with one’s family.

Costa Rica has been largely recognized as a democratic and politically stable country in a region (Central America) characterized by instability, dictatorships, and social inequality. Several social and institutional problems have risen during the last decades, but the country still maintains good social and health indicators. Historical Dictionary of Costa Rica contains a chronology, an introduction, appendixes, and an extensive bibliography. The dictionary section has over 1,000 cross-referenced entries on important personalities, politics, economy, foreign relations, religion, and culture. This book is an excellent resource for students, researchers, and anyone wanting to know more about Costa Rica.

Ocular Pharmacotherapy concerns the use of drugs to treat diseases of the eye. This book, from the Chairman of Ophthalmology at Complutense University in Madrid, is an essential resource for residents, students and practising ophthalmologists. It provides key information regarding both the basic pharmacology of ophthalmic drugs and their use in clinical practice. The comprehensive text consists of twenty-six chapters, incorporating an extensive review across six chapters of various anti-microbial treatments. These include commercially available antibiotics, fortified topical antibiotics, intravitreal, subconjunctival, intracorneal and oral antibiotics, antivirals, antifungals and antiparasitics. It also includes a detailed appendix on the treatment of uveitis and covers new ophthalmic diagnostic and therapeutic formulations and delivery systems, which have been developed in recent years. Over 140 full colour images, including numerous high-quality clinical photographs, charts and tables, enhance understanding. Ocular Pharmacotherapy provides an excellent point of reference to assist in making initial decisions on treatment, for students and professionals alike. Key Points Up-to-date information on new developments in ocular pharmacotherapy Extensive review of anti-microbial treatments Highly illustrated with clinical photographs, charts and tables Authored by a recognised ophthalmic specialist from Spain

Opinions of specialized labor courts differ, but labor justice undoubtedly represented a decisive moment in worker 's history. When and how did these courts take shape? Why did their originators consider them necessary? Leon Fink and Juan Manuel Palacio present essays that address these essential questions. Ranging from Canada and the United States to Chile and Argentina, the authors search for common factors in the appearance of labor courts while recognizing the specific character of the creative process in each nation. Their transnational and comparative approach advances a global perspective on the various mechanisms for regulating industrial relations and resolving labor conflicts. The result is the first country-by-country study of its kind, one that addresses a defining shift in law in the first half of the twentieth century. Contributors: Rossana Barragan Romano, Angela de Castro Gomes, David Diaz-Arias, Leon Fink, Frank Luce, Diego Ortuzar, German Palacio, Juan Manuel Palacio, William Suarez-Potts, Fernando Teixeira da Silva, Victor Uribe-Uran, Angela Vergara, and Ronny J. Viales-Hurtado.