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Treats certain problems and methods of theoretical physics and
astrophysics which are associated with microscopic and macroscopic
electrodynamics and material concerning the theory of transition
radiation and transition scattering.
This book is intended as a supplementary text to the standard
course books on theoretical physics and astrophysics, addressing
applications and selected problems in theoretical physics and
astrophysics, most of which are to a greater or lesser extent
associated with electrodynamics.
Serpins (serine protease inhibitors) are a superfamily of proteins
whose physiologi- cal action is primarily targeted to inhibiting
serine proteases. There are instances where serpins are not
inhibitors (and can carry steroid hormones for instance), yet key
structural and functional elements found in all serpins are
maintained in these 'non-inhibitor' ser- pins. Many serpins have
well-described biological properties which influence pathophysi-
ological events, including: antithrombin (historically called
antithrombin III), ai-protease inhibitor (historically called
ai-antitrypsin), and plasminogen activator inhibitor-I, just to
mention a few. A deficiency or defect in antithrombin leads to
venous thromboembolic disease, while a deficiency or defect in
ai-protease inhibitor is associated with chronic obstructive
pulmonary emphysema. In contrast, it has been suggested that
increased levels of plasminogen activator inhibitor-l may be a
predisposition to myocardial infarction. The list goes on for each
of our own "favorite" serpin. The biological roles found for
serpins are key participants in almost every physiological event.
In other words, serine proteases are needed for many events in
biology and the role of serpins to down regulate these pro- teases
is essential. Thus, just using these three examples above for
serpins and their patho- physiological roles reminds us that the
medical costs to control such events is significant worldwide.
Written by the leading names in pediatric oncology and hematology,
Nathan and Oski's Hematology and Oncology of Infancy and Childhood
offers you the essential tools you need to overcome the unique
challenges and complexities of childhood cancers and hematologic
disorders. Meticulously updated, this exciting full-color,
two-volume set brings together the pathophysiology of disease with
detailed clinical guidance to provide you with the most
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and treating children. Form a definitive diagnosis and create the
best treatment plans possible with comprehensive coverage of all
pediatric cancers, including less-common tumors, as well as all
hematologic disorders, including newly recognized ones. Develop a
thorough, understanding of the underlying science of diseases
through summaries of relevant pathophysiology balanced with clear,
practical clinical guidance. Nathan and Oski's is the only
comprehensive product on the market that relates pathophysiology in
such depth to hematologic and oncologic diseases affecting
children. Quickly and effortlessly access the key information you
need with the help of a consistent organization from chapter to
chapter and from volume to volume. Stay at the forefront of your
field thanks to new and revised chapters covering topics such as
paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases,
childhood genetic predisposition to cancer, and oncology
informatics. Learn about the latest breakthroughs in diagnosis and
management, making this the most complete guide in pediatric
hematology and oncology. Discover the latest in focused molecularly
targeted therapies derived from the exponential growth of knowledge
about basic biology and genetics underlying the field. Rely on it
anytime, anywhere! Access the full text, images, and more at Expert
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This scarce antiquarian book is a selection from Kessinger
PublishingA AcentsAcentsa A-Acentsa Acentss Legacy Reprint Series.
Due to its age, it may contain imperfections such as marks,
notations, marginalia and flawed pages. Because we believe this
work is culturally important, we have made it available as part of
our commitment to protecting, preserving, and promoting the world's
literature. Kessinger Publishing is the place to find hundreds of
thousands of rare and hard-to-find books with something of intere
This scarce antiquarian book is a selection from Kessinger
PublishingA AcentsAcentsa A-Acentsa Acentss Legacy Reprint Series.
Due to its age, it may contain imperfections such as marks,
notations, marginalia and flawed pages. Because we believe this
work is culturally important, we have made it available as part of
our commitment to protecting, preserving, and promoting the world's
literature. Kessinger Publishing is the place to find hundreds of
thousands of rare and hard-to-find books with something of intere
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