This modern illustrated textbook for biologists provides an introduction to the key ideas of sampling, experimental design and statistical analysis. It provides all that will be required in an introductory statistics course for biology undergraduates. The book covers the material in an accessible format, supplemented by illustrations which reinforce the central importance of employing familiar biological examples. "An Introduction to Experimental Design and Statistics for Biology" develops its explanation of statistical concepts and the principles of procedures through the use of common-sense, non-mathematical explanations, based on an extensive use of diagrams. These are then followed by the relevant formulae and illustrated by a worked example located clearly and distinctly in the text. Examples are drawn from all areas of biology, from biochemistry to ecology and from cell to animal biology, locating familiar biological concepts firmly at the centre of the development of statistical and experimental skill. The book is a readable and accessible introduction to statistics with extensive use of diagrammatic explanations and a wide range of biological examples. There are easy to use

A framework for financial market modeling, the benchmark approach extends beyond standard risk neutral pricing theory. It permits a unified treatment of portfolio optimization, derivative pricing, integrated risk management and insurance risk modeling. This book presents the necessary mathematical tools, followed by a thorough introduction to financial modeling under the benchmark approach, explaining various quantitative methods for the fair pricing and hedging of derivatives.

The benchmark approach provides a general framework for financial market modeling, which extends beyond the standard risk-neutral pricing theory. It permits a unified treatment of portfolio optimization, derivative pricing, integrated risk management and insurance risk modeling. The existence of an equivalent risk-neutral pricing measure is not required. Instead, it leads to pricing formulae with respect to the real-world probability measure. This yields important modeling freedom which turns out to be necessary for the derivation of realistic, parsimonious market models. The first part of the book describes the necessary tools from probability theory, statistics, stochastic calculus and the theory of stochastic differential equations with jumps. The second part is devoted to financial modeling by the benchmark approach. Various quantitative methods for the real-world pricing and hedging of derivatives are explained. The general framework is used to provide an understanding of the nature of stochastic volatility. The book is intended for a wide audience that includes quantitative analysts, postgraduate students and practitioners in finance, economics and insurance. It aims to be a self-contained, accessible but mathematically rigorous introduction to quantitative finance for readers that have a reasonable mathematical or quantitative background. Finally, the book should stimulate interest in the benchmark approach by describing some of its power and wide applicability.

In Longshot, investigative journalist David Heath takes readers inside the small group of scientists whose groundbreaking work was once largely dismissed but whose feat will now eclipse the importance of Jonas Salk's polio vaccine in medical history. With never-before-reported details, Heath reveals how these scientists overcame countless obstacles to give the world an unprecedented head start when we needed a COVID-19 vaccine. The story really begins in the 1990s, with a series of discoveries that were timed perfectly to prepare us for the worst pandemic since 1918. Readers will meet Katalin Kariko, who made it possible to use messenger RNA in vaccines but struggled for years just to hang on to her job. There's also Derrick Rossi, who leveraged Kariko's work to found Moderna but was eventually expelled from his company. And then there's Barney Graham at the National Institutes of Health, who had a career-long obsession with solving the riddle of why two toddlers died in a vaccine trial in 1966, a tragedy that ultimately led to a critical breakthrough in vaccine science. With both foresight and luck, Graham and these other crucial scientists set the course for a coronavirus vaccine years before COVID-19 emerged in Wuhan, China. The author draws on hundreds of hours of interviews with key players to tell the definitive story about how the race to create the vaccine sparked a revolution in medical science.

This dictionary provides a valency description of English verbs, nouns and adjectives. Each entry contains a comprehensive list of the complementation patterns identified on the basis of the largest corpus of English available at the present time. All examples are taken directly from the COBUILD/Birmingham corpus. The valency description comprises statements about the quantitative valency of the lexical units established, an inventory of their obligatory, contextually optional and purely optional complements as well as systematic information on the semantic and collocational properties of the complements. An outline of the model of valency theory used in this dictionary is provided in the introduction. Key Features unique reference work with no comparable publication on the market English is the world's most important lingua franca and the most frequently learned second language

This paper is the fourth of several that have been proposed with an aim of contributing to the body of knowledge related to the subject of ceramic wares, which have been recovered from the Lower Columbia River region in Southwest Washington State and are commonly referred to as Shoto Clay or Lake River Ceramics.

This paper is the third of several that have been proposed with an aim of contributing to the body of knowledge related to the subject of ceramic wares, which have been recovered from the Lower Columbia River region in Southwest Washington State and are commonly referred to as Shoto Clay or Lake River Ceramics. Previous research and reporting on this subject has been limited due to a lack of professionally lead excavations and the limited availability of wares from which scientific study might be made.

This is a story of fiction but inspired by the love of trucking and simple rural farm life as it was in the 50s and 60s. A few hours east of Fort Stockton, Texas, Julie saw the sign indicating she was still a long way from San Antonio. Her eyes felt tired. Several miles back, she had nodded off just a second, and it scared her so bad she almost went off the road into a rocky hillside. Second thoughts haunted her mind about the decision she had made to try for the Alamo city tonight. It was now 11:00 PM and the rain hadn't let up making the road almost impossible to see. She cranked up the heater as the outside temperature dropped considerably colder the further east she traveled. She picked up a Del Rio station on the radio and turned the volume up to keep the cab filled with noise. The country music eased her tired mind as the song play-ing was one of her favorites "yeah," she thought "that's me, Julie Dickinson with nothing but eighteen wheels under my seat and miles of highway ahead."

This paper is the first of several that have been proposed with an aim of contributing to the body of knowledge related to the subject of ceramic wares, which have been recovered from the Lower Columbia River region in Southwest Washington State and are commonly referred to as Shoto Clay or Lake River Ceramics.

This paper is the second of several that have been proposed with an aim of contributing to the body of knowledge related to the subject of ceramic wares, which have been recovered from the Lower Columbia River region in Southwest Washington State and are commonly referred to as Shoto Clay or Lake River Ceramics. Previous research and reporting on this subject has been limited due to a lack of professionally lead excavations and the limited availability of wares from which scientific study might be made.

For eleven years David sought out love and an end to writer's block. Meeting the person to whom this book was dedicated, unlocked doors thought closed forever. However, when fate ended that relationship the pool of emotions overflowed. Perhaps you can relate to or understand the author's emotions throughout this book. Life Love and Regrets if full of all three both emotions and outlooks of the author.