Computer animated action movie featuring Marvel Comics superheroes Iron Man (voice of Adrian Pasdar) and Hulk (Fred Tatasciore). When Earth comes under attack from powerful monster Zzzax (Dee Bradley Baker), Iron Man and Hulk combine their unique strengths in the hope of defeating the enemy and saving the world. But can they learn to work as a team despite their differences?

Prove It With Figures displays some of the tools of the social and statistical sciences that have been applied in the courtroom and to the study of questions of legal importance. It explains how researchers can extract the most valuable and reliable data that can conveniently be made available, and how these efforts sometimes go awry. In the tradition of Zeisel's standard work "Say It with Figures," the authors clarify, in non-technical language, some of the basic problems common to all efforts to discern cause-and-effect relationships. Designed as a textbook for law students who seek an appreciation of the power and limits of empirical methods, this is also a useful reference for lawyers, policymakers, and members of the public who would like to improve their critical understanding of the statistics presented to them. The many case histories include analyses of the death penalty, jury selection, employment discrimination, mass torts, and DNA profiling.

Substance Abuse and Addiction Research: Methodology, Mechanisms, and Therapeutics is an up-to-date, comprehensive, practical book on research methodologies for substance abuse and addiction that is intended for researchers and consumers of research information at all levels. The book is divided into four major sections, including an Introduction, Research Methodology for clinical trials, animal research and retrospective studies, Mechanisms of Abuse and Addiction, and Investigative Therapeutics: Designing and Measuring Outcomes. It serves a source for addressing all aspects of research design, methods and analysis within the context of the field of opioids, alcohol and other substances. The book covers what is known in the field of quantitative and qualitative research methods, provides future directions, and introduces new models for investigation. It is organized around a translational science framework, with the contents addressing substance use/addiction research in the context of epidemiology, etiology, intervention efficacy and effectiveness, and implementation of evidence-informed interventions.

This issue of Anesthesiology Clinics focuses on Pharmacology. Editor Alan Kaye has assembled an expert team of authors on topics such as: Ketorolac, Oxymorphone and Tapentadol; Anticoagulation and Neuraxial/Peripheral Anesthesia; Pharmacologic Update on Antiemetics: Total parenteral nutrition/enteral nutrition in the ICU, Evolving Concepts; Reversal of Anticoagulants and Anesthesia Considerations; Non-opioids Intravenous or Oral Analgesics for Perioperative Pain Management, Update; Uterotonic Medications and Anesthesia Considerations: oxytocin, misoprostol, methylergonovine, carboprost; Pulmonary Vascular Mediating Drugs, Evolving Concepts; Alpha 2 Modulators and Anesthesia Considerations; Pharmacologic Considerations of Anesthetic Agents in the Obese Patient; Pharmacologic Considerations of Anesthetic Agents in the Geriatric Patient; Pharmacologic Considerations of Anesthetic Agents in the Pediatric Patient; Anesthesia CV Drug Update; Pharmacogenomics: Anesthesia; Pharmacogenomics: Pain; Novel anticoagulants; Novel anesthetic agents; Novel opioids; Pharmacology of Newer Local anesthetics; Pharmacology of Nonsteroidal Antiinflammatory and Steroid Medications. Implications for Anesthesia or Unique Associated Risks; Pharmacology of Octreotide. Implications for Anesthesia and Associated Risks.

Effective leadership is critical to ensuring safety, efficiency and maximum productivity in the operating room (OR). This practical, evidence-based book unpicks the dynamics of a successful OR environment to underline the key techniques for management of policies, systems, staff members and teams. Fully updated to include recent clinical guidelines, the book provides the 'A-Z' of OR management, including sections on metrics, scheduling, human resource management, leadership principles, economics, quality assurance, recovery and ambulatory practice. New chapters include future healthcare models, emergency preparedness and budgets amongst other topics. Written by authors with unrivalled experience in the field, chapters are laid out in an easy and clinically helpful format to assist learning, and real-life case studies cover seventy-three different clinically relevant pain topics. This book is an essential guide for anyone working in the OR including anaesthesiologists, surgeons, nurses, and administrators.

This is a practical guide to the evidence-based diagnosis and management of orofacial pain. It covers common clinical presentations of acute and chronic orofacial pain and summarizes clinically relevant neurobiology. Because diagnosing orofacial pain can be a challenge, the book describes the appropriate history-taking methods, detailed examinations, and relevant tests that will help clinicians to work through the differential diagnosis. Effective medical, surgical, and behavioral approaches are presented, and the importance of a multimodal approach is consistently emphasized throughout the book. The target audience includes pain physicians, anesthesiologists, dentists, neurologists, nurse practitioners, and physician's assistants.

Prove It With Figures displays some of the tools of the social and statistical sciences that have been applied in the courtroom and to the study of questions of legal importance. It explains how researchers can extract the most valuable and reliable data that can conveniently be made available, and how these efforts sometimes go awry. In the tradition of Zeisel's standard work "Say It with Figures," the authors clarify, in non-technical language, some of the basic problems common to all efforts to discern cause-and-effect relationships. Designed as a textbook for law students who seek an appreciation of the power and limits of empirical methods, this is also a useful reference for lawyers, policymakers, and members of the public who would like to improve their critical understanding of the statistics presented to them. The many case histories include analyses of the death penalty, jury selection, employment discrimination, mass torts, and DNA profiling.

"David Kaye's book is crucial to understanding the tactics, rhetoric and stakes in one of the most consequential free speech debates in human history." -Cory Doctorow, author of Radicalized, Walkaway and Little Brother The internet was designed to be a kind of free-speech paradise, but a lot of the material on it turned out to incite violence, spread untruth, and promote hate. Over the years, three American behemoths-Facebook, YouTube and Twitter-became the way most of the world experiences the internet, and therefore the conveyors of much of its disturbing material. What should be done about this enormous problem? Should the giant social media platforms police the content themselves, as is the norm in the U.S., or should governments and international organizations regulate the internet, as many are demanding in Europe? How do we keep from helping authoritarian regimes to censor all criticisms of themselves? David Kaye has been has been at the center of the discussions of these issues for years. He takes us behind the scenes, from Facebook's "mini-legislative" meetings, to the European Commission's closed-door negotiations, and introduces us to journalists, activists, and content moderators whose stories bring clarity and urgency to the topic of censorship. Speech Police is the most comprehensive and insightful treatment of the subject thus far, and reminds us of the importance of maintaining the internet's original commitment to free speech, free of any company's or government's absolute control, while finding ways to modulate its worst aspects.

This comprehensive book is written to inform and improve outcomes of patients in need of blood management during surgical procedures. Information is presented in an accessible format, allowing for immediate use in clinical practice. Beginning with an overview of the history of blood transfusions, early chapters present the foundational information needed to comprehend information in later chapters. Nuanced procedures, drugs, and techniques are covered, including new biologicals to assist clotting and blood substitutes. Further discussions focus on potential complications seen in blood transfusions, such as diseases of the coagulation system, pathogen transmissions, and acute lung injuries. Chapters also examine the complexities of treating specific demographics, of which include the geriatric patient and patients suffering from substance abuse. Essentials of Blood Product Management in Anesthesia Practice is an invaluable guide for anesthesiologists, surgeons, trauma physicians, and solid organ transplant providers.

This book is a comprehensive, focused resource on intraoperative neurophysiological monitoring (IOM). This rapidly evolving field has created a demand for an up-to-date book such as this that builds on foundational concepts necessary to the practice of IOM in the context of anatomy and physiology. Each chapter is designed to not only inform the reader, but to also test the reader on the information presented - therefore promoting practical, problem-based learning. Surpassing the quality of its successful predecessor, Principles of Neurophysiological Assessment, Mapping, and Monitoring, Second Edition, is positioned to suit the needs of residents and fellows studying for the IOM certificate programs, physicians and anesthesiologists practicing IOM, and neurotechnologists both experienced and in training.

Essentials of Palliative Care is a to-the-point, clinically oriented resource for all members of the multidisciplinary palliative care team and trainees. It covers practical clinical topics, including assessment of the patient and pain and symptom management, and practical non-medical topics central to providing effective palliative care, including psychological management, guidance on how to help patients and their families through the many healthcare decision points they face, and sensitivity to the goals and culture of the patient. Review questions, with detailed answers, provide a convenient way for readers to test their knowledge.

Features:

. Concise, comprehensive, clinically focused

. Multiple choice review questions, with detailed answers

. Expert contributors from leading institutions

. Coordination of care by palliative care team a major focus

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The recent advances in the clinical practice of anesthesiology have increased the need for a new state-of-the art anesthesia handbook for practicing anesthesiologists, trainees and students. This practical book provides a modern, clinically focused guide for any clinical question related to anesthesia care, presenting comprehensive, yet succinct knowledge from experts in the field. It describes the best practice in a concise yet easily digestible format and features numerous tables and figures, a bulleted points/outline format, and algorithms allowing for rapid assimilation of key information. New techniques and common procedures are also covered in detail. This up-to-date pocketbook is perfect for quick reference in the operating room, providing rapid access to evidence-based clinical content covering the full breadth of the field, including pediatric, obstetric, cardiac and regional anesthesia sections. In addition to daily clinical practice, the book serves also as a convenient companion for board review and recertification exam preparation.

Scholars from across law and internet and media studies examine the human rights implications of today's platform society. Today such companies as Apple, Facebook, Google, Microsoft, and Twitter play an increasingly important role in how users form and express opinions, encounter information, debate, disagree, mobilize, and maintain their privacy. What are the human rights implications of an online domain managed by privately owned platforms? According to the Guiding Principles on Business and Human Rights, adopted by the UN Human Right Council in 2011, businesses have a responsibility to respect human rights and to carry out human rights due diligence. But this goal is dependent on the willingness of states to encode such norms into business regulations and of companies to comply. In this volume, contributors from across law and internet and media studies examine the state of human rights in today's platform society. The contributors consider the "datafication" of society, including the economic model of data extraction and the conceptualization of privacy. They examine online advertising, content moderation, corporate storytelling around human rights, and other platform practices. Finally, they discuss the relationship between human rights law and private actors, addressing such issues as private companies' human rights responsibilities and content regulation. Contributors Anja Bechmann, Fernando Bermejo, Agnes Callamard, Mikkel Flyverbom, Rikke Frank Jorgensen, Molly K. Land, Tarlach McGonagle, Jens-Erik Mai, Joris van Hoboken, Glen Whelan, Jillian C. York, Shoshana Zuboff, Ethan Zuckerman Open access edition published with generous support from Knowledge Unlatched and the Danish Council for Independent Research.

This comprehensive book is written to inform and improve outcomes of patients in need of blood management during surgical procedures. Information is presented in an accessible format, allowing for immediate use in clinical practice. Beginning with an overview of the history of blood transfusions, early chapters present the foundational information needed to comprehend information in later chapters. Nuanced procedures, drugs, and techniques are covered, including new biologicals to assist clotting and blood substitutes. Further discussions focus on potential complications seen in blood transfusions, such as diseases of the coagulation system, pathogen transmissions, and acute lung injuries. Chapters also examine the complexities of treating specific demographics, of which include the geriatric patient and patients suffering from substance abuse. Essentials of Blood Product Management in Anesthesia Practice is an invaluable guide for anesthesiologists, surgeons, trauma physicians, and solid organ transplant providers.

Edited by internationally recognized pain experts, this unique book describes 73 real life clinical cases, each followed by discussion of pathogenesis, work-up, differential diagnosis and treatment options. Cases are divided into seven sub-topics: neurologic disorders, spinal disorders, musculoskeletal pain, visceral pain, headache and facial pain, cancer pain, and special topics such as pain in children and older adults. Discussions follow a question-and-answer format, facilitating learning and also enabling self-testing. Chapters are written by the foremost national and international leaders in the field of pain management, many of whom are pain program directors. Case Studies in Pain Management is an excellent learning source for trainees in pain management and a 'must read' for pain practitioners.

When by chance, Cheyanne a street-wise 25 year old transsexual prostitute recently released from prison, meets Evan, a naive young man ambiguous about his sexual identity, the elements are in place for this erotic thriller.The story fueled by newly inherited wealth, greed, abundant use of crystal methamphetamine, sexual appetites without boundaries and even murder will make the reader laugh or at times cry.Join Cheyanne and Evan in their journey from the street sex trade on LA's Santa Monica Boulevard to sex celebrity style in the Hollywood Hills and New York City.Read her story as it might have been told to the author by Cheyanne.For readers actually living in the transgendered world, meet new heroes and heroines.For others who chance upon this book you may gain a new understanding and acceptance of a lifestyle you wondered about.

In anesthesiology, pain medicine, and critical care, practitioners at all levels need help to stay current with the continually evolving drug knowledge-base, and trainees need tools to prepare for in-training and board exams that increasingly test their knowledge of pharmacology. This practical book is aimed at both readerships. It features a unique and practical chapter on the United States Food and Drug Administration (FDA) "black box" warnings that describe what safety precautions should be taken with commonly used drugs. The editors and contributors are pharmacology experts representing a cross-section of clinical specialties and institutions in the United States and include pharmacologists, pharmacists, as well as physicians.

First Practical Guide to Integrating Risk Management, Business Continuity Management and Corporate Governance From Two World-Renowned BCM Pioneers Who Have Served on the British Standards Institution (BSI) Team Creating a British and International Standard for Risk Management. The U.S. Department of Homeland Security (DHS) is currently developing disaster preparedness standards for businesses. DHS is incorporating language from the British Standards Institution (BSI) because it "provides a management systems approach to business continuity and integrates risk management disciplines and processes." The two authors of this now classic text in the field have been directly involved in developing those BSI standards. Here they bring you a distillation of their worldwide experience in pioneering the integration of the disciplines of risk management and business continuity. This practical guide is endorsed by: * * * The Business Continuity Institute * * * The Institute for Risk Management * * * Disaster Recovery Institute International It includes numerous helpful features: * * * Chapter objectives, summaries and bibliographies; charts, sample forms, checklists throughout * * * Plentiful case studies, in boxed text, drawn from enterprises around the globe, including the UK, US, Europe, Australia, Asia, etc. * * * Boxed inserts summarizing key concepts * * * Glossy of 150 risk management and business continuity terms * * * Timely topics, including stakeholder management, supplier management, outsourcing, the people factor, technology recovery, and communication, both internally and externally. * * * Wide range of challenges, including supply chain disruptions, media and brand attack, product contamination and product recall, bomb threats, chemical and biological threats, etc. * * * Instructions for designing/executing team exercises with role playing to rehearse scenarios * * * Guidance on how to develop a business continuity plan, including a Business Impact Analysis * * * Ideal for senior undergraduate, MBA, certificate, corporate training programs; in use at 50+ campuses worldwide * * * Instructor Materials on CD, including PowerPoint slides and syllabus for 12-week course with lecture outlines/notes, quizzes, reading assignments, discussion topics, projects * * * Authors with extensive international experience in all aspects of risk management and business continuity, having worked with organizations in a combined total of 50 countries The authors' message is that risk management has become a strategic tool in managing all risk across an organization, and that BCM forms one more important tool in a much wider and coordinated risk management program. They are now complementary disciplines that must be understood and supported by your organization as a whole, including CEO's, directors, non- executive directors, risk managers, continuity managers, internal and external auditors, investment managers, compliance managers, finance directors, human resource managers, project managers, regulators, corporate trainers and other stakeholders. After discussing the relationship between risk management and BCM, the authors take the reader through the business continuity management cycle: how to understand the organization and its culture; continuity strategies; how to develop and implement a business continuity response, including developing a Business Impact Analysis; building and embedding a business continuity culture; testing/exercising a plan, along with benchmarking, maintenance and audit. "This book is a must read for those senior managers, risk managers and continuity managers who have the vision to see both the new opportunities and the new responsibilities of business continuity management." - George J. Mitchell, Chairman, DLA Piper Rudnick Gray Cary; Former Senate Majority Leader and U.S. Senator for Maine.

A unique how-to guide for spine surgeons on state-of-the-art computer-assisted navigation and robotic surgery techniques The past decade has seen major advances in image-guided spine surgery techniques, with robotically assisted approaches emerging in the last five years. While early adopters of this technology paved the way for more widespread use of navigated and robotic systems, barriers still exist. Navigation and Robotics in Spine Surgery by master spine surgeon Alexander Vaccaro and esteemed co-editors Jaykar Panchmatia, I. David Kaye, and Srinivas Prasad addresses existing issues such as the perception of increased upfront costs, intrusion on current workflow, and a lack of understanding about the potential ways these technologies can enhance the surgical experience and improve patient outcomes. Organized into six sections, the book starts with evidence-based fundamentals of navigated spine surgery and robotics including discussion of instrumentation and mechanics. Sections 2-5 serve as a surgical handbook for spine surgeons who wish to introduce these technologies into practice or augment their current repertoire with more complex techniques. Topics range from more routine procedures such as navigated and robotic minimally invasive TLIF to complex approaches like intraoperative ultrasound guided intradural spinal tumor resection. The final section looks at future directions and potential new applications for these technologies. Key Highlights An impressive group of international spine surgeons who pioneered navigation and robotic surgery techniques share invaluable tricks of the trade Discussion of fluoroscopy- and intraoperative CT-based platforms, applications for intraoperative sonography, and radiation exposure and minimization strategies Special topics include OR set-up and workflow, surmounting the learning curve, artificial intelligence, and lessons learned from other industries Procedural videos demonstrate the benefits of computer-assisted navigation and robotic techniques This book is essential reading for orthopaedic surgery and neurosurgery residents and spine fellows who wish to learn about and incorporate these technologies into practice. Seasoned spine surgeons seeking to expand the scope of their navigated/robotic practice will benefit from chapters detailing advanced approaches. This book includes complimentary access to a digital copy on https://medone.thieme.com.

Perioperative Management in Robotic Surgery covers perioperative considerations for robot-assisted surgery (RAS), from preoperative through to postoperative. This is the first extensive, evidence-based, clinical work covering the perioperative management of commonly performed and emerging RAS. Included inside are discussions of surgical procedures, preoperative evaluation, patient selection, common emergencies, complications, pain management and recovery (including same day surgery). There are also reviews of patient management, the basics of various procedures and techniques, useful patient care protocols, as well as an overview of the perioperative issues that are unique to any given RAS procedure. The book is written for anesthesiologists, surgeons, and other perioperative physicians - as well as allied health professionals, nurses, and physician assistants who assist during RAS procedures and help manage patients during the perioperative period.

The management of pain can often be achieved by medications, physical therapies, or by various procedural techniques that have evolved in recent decades. With the trend towards more outpatient surgeries and less invasive surgeries to decrease perioperative risk, perioperative time, and costs, the practice of anesthesia is evolving to utilize regional anesthesia techniques both for inpatients and outpatients. Regional anesthesia is being performed for outpatient surgeries, obstetric anesthesia, trauma, chronic pain states, and for acute post-operative pain management. Therefore, it is paramount for physicians and nurses practicing anesthesia to understand the essentials of regional anesthesia, its evolving techniques, and appropriate utilization of modern equipment and technology to provide care safely. Essentials of Regional Anesthesia, Second edition, is a concise, up-to-date, evidence-based handbook that enables every resident, physician and nurse to understand the basics of regional anesthesia and the standard of care guidelines for the practice of regional anesthesia in a comprehensive fashion. This new edition includes: * Updated and new chapters on Ambulatory, Critical Care, and Obstetrics topics * Full color, clear, detailed, anatomic drawings * Clinically relevant, practical aspects of regional anesthesia * International contributing authors who are experts in their field * Latest ultrasound techniques and images Review of 1st edition: "There are many books available on regional anesthesia, and the trend is either to focus on illustrations, forgoing any discussion, or on text descriptions, making them bulky and hard to read. This book maintains that perfect balance between text and illustrations. It is truly a master companion book on regional anesthesia." (Tariq M. Malik, Doody's Book Reviews, April, 2012)