The British Royal Family is dispatched en masse after being electrocuted during a family portrait. A search for a successor turns up Ralph Jones (John Goodman), a Las Vegas lounge singer, as the unlikely next-in-line. Before long, Buckingham Palace resembles a funfair and Lord Graves (John Hurt) is plotting King Ralph's demise.

Horror following two college friends who take part in a pharmaceutical experiment during the Christmas break in order to earn some money. The participants are locked up in a secluded hospital during the two week trial but they soon begin to display violent side effects. The doctors are unable to maintain control of the situation and the experiment gets out of hand, putting everyone at risk.