|
Showing 1 - 12 of
12 matches in All Departments
Polymers are essential to biology because they can have enough
stable degrees of freedom to store the molecular code of heredity
and to express the sequences needed to manufacture new molecules.
Through these they perform or control virtually every function in
life. Although some biopolymers are created and spend their entire
career in the relatively large free space inside cells or
organelles, many biopolymers must migrate through a narrow
passageway to get to their targeted destination. This suggests the
questions: How does confining a polymer affect its behavior and
function? What does that tell us about the interactions between the
monomers that comprise the polymer and the molecules that confine
it? Can we design and build devices that mimic the functions of
these nanoscale systems? The NATO Advanced Research Workshop
brought together for four days in Bikal, Hungary over forty experts
in experimental and theoretical biophysics, molecular biology,
biophysical chemistry, and biochemistry interested in these
questions. Their papers collected in this book provide insight on
biological processes involving confinement and form a basis for new
biotechnological applications using polymers. In his paper Edmund
DiMarzio asks: What is so special about polymers? Why are polymers
so prevalent in living things? The chemist says the reason is that
a protein made of N amino acids can have any of 20 different kinds
at each position along the chain, resulting in 20 N different
polymers, and that the complexity of life lies in this variety.
Membrane permeability is fundamental to all cell biology and
subcellular biology. The cell exists as a closed unit. Import and
export depend upon a number of sophisticated mechanisms, such as
active transport, endocytosis, exocytosis, and passive diffusion.
These systems are critical for the normal housekeeping
physiological functions. However, access to the cell is also taken
advantage of by toxic microbes (such as cholera or ptomaine) and
when designing drugs.
Ernest Overton, one of the pioneers in lipid membrane research, put
forward the first comprehensive theory of lipid membrane structure.
His most quoted paper on the osmotic properties of cells laid the
foundation for the modern concepts of membrane function, most
notably important in anesthesia.
This book is designed to celebrate the centennial anniversary (in
the first chapter) of Overton's work. Subsequent chapters present
readers with up-to-date concepts of membrane structure and function
and the challenge they pose for new explorations.
Key Features
* Provides an historical perspective of Overton's contributions to
the theory of narcosis
* Presents an overview of each permeability mechanism, including
active transport, endocytosis, exocytosis, and passive diffusion
Update your knowledge of the chemical, biological, and physical
properties of liquid-liquid interfaces with Liquid-Liquid
Interfaces: Theory and Methods. This valuable reference presents a
broadly based account of current research in liquid-liquid
interfaces and is ideal for researchers, teachers, and students.
Internationally recognized investigators of electrochemical,
biological, and photochemical effects in interfacial phenomena
share their own research results and extensively review the results
of others working in their area. Because of its unusually wide
breadth, this book has something for everyone interested in
liquid-liquid interfaces. Topics include interfacial and phase
transfer catalysis, electrochemistry and colloidal chemistry, ion
and electron transport processes, molecular dynamics,
electroanalysis, liquid membranes, emulsions, pharmacology, and
artificial photosynthesis. Enlightening discussions explore
biotechnological applications, such as drug delivery, separation
and purification of nuclear waste, catalysis, mineral extraction
processes, and the manufacturing of biosensors and ion-selective
electrodes. Liquid-Liquid Interfaces: Theory and Methods is a
well-written, informative, one-stop resource that will save you
time and energy in your search for the latest information on
liquid-liquid interfaces.
Update your knowledge of the chemical, biological, and physical
properties of liquid-liquid interfaces with Liquid-Liquid
Interfaces: Theory and Methods. This valuable reference presents a
broadly based account of current research in liquid-liquid
interfaces and is ideal for researchers, teachers, and students.
Internationally recognized investigators of electrochemical,
biological, and photochemical effects in interfacial phenomena
share their own research results and extensively review the results
of others working in their area. Because of its unusually wide
breadth, this book has something for everyone interested in
liquid-liquid interfaces. Topics include interfacial and phase
transfer catalysis, electrochemistry and colloidal chemistry, ion
and electron transport processes, molecular dynamics,
electroanalysis, liquid membranes, emulsions, pharmacology, and
artificial photosynthesis. Enlightening discussions explore
biotechnological applications, such as drug delivery, separation
and purification of nuclear waste, catalysis, mineral extraction
processes, and the manufacturing of biosensors and ion-selective
electrodes. Liquid-Liquid Interfaces: Theory and Methods is a
well-written, informative, one-stop resource that will save you
time and energy in your search for the latest information on
liquid-liquid interfaces.
Polymers are essential to biology because they can have enough
stable degrees of freedom to store the molecular code of heredity
and to express the sequences needed to manufacture new molecules.
Through these they perform or control virtually every function in
life. Although some biopolymers are created and spend their entire
career in the relatively large free space inside cells or
organelles, many biopolymers must migrate through a narrow
passageway to get to their targeted destination. This suggests the
questions: How does confining a polymer affect its behavior and
function? What does that tell us about the interactions between the
monomers that comprise the polymer and the molecules that confine
it? Can we design and build devices that mimic the functions of
these nanoscale systems? The NATO Advanced Research Workshop
brought together for four days in Bikal, Hungary over forty experts
in experimental and theoretical biophysics, molecular biology,
biophysical chemistry, and biochemistry interested in these
questions. Their papers collected in this book provide insight on
biological processes involving confinement and form a basis for new
biotechnological applications using polymers. In his paper Edmund
DiMarzio asks: What is so special about polymers? Why are polymers
so prevalent in living things? The chemist says the reason is that
a protein made of N amino acids can have any of 20 different kinds
at each position along the chain, resulting in 20 N different
polymers, and that the complexity of life lies in this variety.
This is an introductory text and laboratory manual to be used
primarily in undergraduate courses. It is also useful for graduate
students and research scientists who require an introduction to the
theory and methods of nanopore sequencing. The book has clear
explanations of the principles of this emerging technology,
together with instructional material written by experts that
describes how to use a MinION nanopore instrument for sequencing in
research or the classroom.At Harvard University the book serves as
a textbook and lab manual for a university laboratory course
designed to intensify the intellectual experience of incoming
undergraduates while exploring biology as a field of concentration.
Nanopore sequencing is an ideal topic as a path to encourage
students about the range of courses they will take in Biology by
pre-emptively addressing the complaint about having to take a
course in Physics or Maths while majoring in Biology. The book
addresses this complaint by concretely demonstrating the range of
topics - from electricity to biochemistry, protein structure,
molecular engineering, and informatics - that a student will have
to master in subsequent courses if he or she is to become a
scientist who truly understands what his or her biology instrument
is measuring when investigating biological phenomena.
Our knowledge of our solar system has passed the point of no
return. Increasingly, it seems possible that scientists will soon
discover how life is created on habitable planets like Earth and
Mars. Scientists have responded to a renewed public interest in the
origin of life with research, but many questions still remain
unanswered in the broader conversation. Other questions can be
answered by the laws of chemistry and physics, but questions
surrounding the origin of life are best answered by reasonable
extrapolations of what scientists know from observing the Earth and
its solar system. Origin of Life: What Everyone Needs to Know (R)
is a comprehensive scientific guide on the origin of life. David W.
Deamer sets out to answer the top forty questions about the origin
of life, including: Where do the atoms of life come from? How old
is Earth? What was the Earth like before life originated? Where
does water come from? How did evolution begin? After he provides
the informational answer for each question, there is a follow-up:
How do we know? This question expands the horizon of the whole
book, and provides scientific reasoning and explanations for
hypotheses surrounding the origin of life. How scientists come to
their conclusions and why we can trust these answers is an
important question, and Deamer provides answers to each big
question surrounding the origin of life, from what it is to why we
should be curious.
This is an introductory text and laboratory manual to be used
primarily in undergraduate courses. It is also useful for graduate
students and research scientists who require an introduction to the
theory and methods of nanopore sequencing. The book has clear
explanations of the principles of this emerging technology,
together with instructional material written by experts that
describes how to use a MinION nanopore instrument for sequencing in
research or the classroom.At Harvard University the book serves as
a textbook and lab manual for a university laboratory course
designed to intensify the intellectual experience of incoming
undergraduates while exploring biology as a field of concentration.
Nanopore sequencing is an ideal topic as a path to encourage
students about the range of courses they will take in Biology by
pre-emptively addressing the complaint about having to take a
course in Physics or Maths while majoring in Biology. The book
addresses this complaint by concretely demonstrating the range of
topics - from electricity to biochemistry, protein structure,
molecular engineering, and informatics - that a student will have
to master in subsequent courses if he or she is to become a
scientist who truly understands what his or her biology instrument
is measuring when investigating biological phenomena.
Our knowledge of our solar system has passed the point of no
return. Increasingly, it seems possible that scientists will soon
discover how life is created on habitable planets like Earth and
Mars. Scientists have responded to a renewed public interest in the
origin of life with research, but many questions still remain
unanswered in the broader conversation. Other questions can be
answered by the laws of chemistry and physics, but questions
surrounding the origin of life are best answered by reasonable
extrapolations of what scientists know from observing the Earth and
its solar system. Origin of Life: What Everyone Needs to Know (R)
is a comprehensive scientific guide on the origin of life. David W.
Deamer sets out to answer the top forty questions about the origin
of life, including: Where do the atoms of life come from? How old
is Earth? What was the Earth like before life originated? Where
does water come from? How did evolution begin? After he provides
the informational answer for each question, there is a follow-up:
How do we know? This question expands the horizon of the whole
book, and provides scientific reasoning and explanations for
hypotheses surrounding the origin of life. How scientists come to
their conclusions and why we can trust these answers is an
important question, and Deamer provides answers to each big
question surrounding the origin of life, from what it is to why we
should be curious.
In Assembling Life, David Deamer addresses questions that are the
cutting edge of research on the origin of life. For instance, how
did non-living organic compounds assemble into the first forms of
primitive cellular life? What was the source of those compounds and
the energy that produced the first nucleic acids? Did life begin in
the ocean or in fresh water on terrestrial land masses? Could life
have begun on Mars? The book provides an overview of conditions on
the early Earth four billion years ago and explains why fresh water
hot springs are a plausible alternative to salty seawater as a site
where life can begin. Deamer describes his studies of organic
compounds that were likely to be available in the prebiotic
environment and the volcanic conditions that can drive chemical
evolution toward the origin of life. The book is not exclusively
Earth-centric, but instead considers whether life could begin
elsewhere in our solar system. Deamer does not propose how life did
begin, because we can never know that with certainty. Instead, his
goal is to understand how life can begin on any habitable planet,
with Earth so far being the only known example.
En El origen de la vida: lo que todo el mundo necesita saber, David
W. Deamer ha escrito una guÍa completa sobre el origen de la vida
que estÁ organizada en tres secciones. La primera secciÓn aborda
preguntas como: ¿De dÓnde provienen los Átomos de la vida?
¿QuÉ edad tiene la Tierra? ¿CÓmo era la Tierra antes de que
comenzara la vida? ¿De dÓnde viene el agua? DespuÉs de que se
responde cada pregunta, hay un seguimiento: ¿CÓmo lo sabemos?
Esto amplÍa el horizonte del libro, explicando cÓmo los
cientÍficos llegan a conclusiones y por quÉ podemos confiar en
estas respuestas. La segunda secciÓn describe cÓmo ciertas
molÉculas orgÁnicas pueden ensamblarse espontÁneamente en
poblaciones de protocÉlulas que pueden someterse a selecciÓn y
evolucionar hacia sistemas vivos primitivos. AquÍ Deamer propone
un concepto verdaderamente novedoso de que la vida no comenzÓ en
el ocÉano sino en fuentes termales de agua dulce en masas de
tierra volcÁnica que se asemejan a Hawaii hoy. El verdadero
conocimiento no es solo lo que sabemos, sino que es igualmente
importante lo que aÚn no sabemos. En la tercera secciÓn, Deamer
enumera las preguntas pendientes que deben abordarse antes de que
podamos finalmente responder a una pregunta fundamental de la
biologÍa: ¿CÓmo puede comenzar la vida? In Origin of Life:
What Everyone Needs to Know , David W. Deamer has written a
comprehensive guide to the origin of life that is organized in
three sections. The first section addresses questions such as:
Where do the atoms of life come from? How old is Earth? What was
the Earth like before life began? Where does water come from? After
each question is answered, there is a follow-up: How do we know?
This expands the horizon of the book, explaining how scientists
reach conclusions and why we can trust these answers. The second
section describes how certain organic molecules can spontaneously
assemble into populations of protocells that can undergo selection
and evolve toward primitive living systems. Here Deamer proposes a
truly novel concept that life did not begin in the ocean but
instead in fresh water hot springs on volcanic land masses
resembling Hawaii today. True knowledge is not just what we know,
but equally important is what we don't yet know. In the third
section Deamer lists the outstanding questions that must be
addressed before we can finally answer a fundamental question of
biology: How can life begin?
|
You may like...
Poor Things
Emma Stone, Mark Ruffalo, …
DVD
R343
Discovery Miles 3 430
Loot
Nadine Gordimer
Paperback
(2)
R383
R318
Discovery Miles 3 180
Loot
Nadine Gordimer
Paperback
(2)
R383
R318
Discovery Miles 3 180
Loot
Nadine Gordimer
Paperback
(2)
R383
R318
Discovery Miles 3 180
|