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Labisia pumila (Kacip Fatimah) is a traditional herb commonly used
by Malay women during peripartum period to make the process of
childbirth easier and also during postpartum period to improve
general condition of mother. Earlier research on Labisia pumila
showed that it has estrogenic-like effect. This randomized, placebo
controlled study was designed to look at the safety profile of
Labisia pumila water extract on postmenopausal women. Pre-study
screening and assessment was done and if subject is eligible,
informed consent taken and baseline investigation was taken
including hematological, liver and renal function, chest x-ray,
ECG, mammography and pap smear. The study duration was six month
and all participants were required to come for visit every two
month. During each visit participants were asked regarding any side
effects of medication or occurrence of per vaginal bleeding. Vital
signs, body mass index and waist hip ratio were measured on every
visit. On visit 4 or last visit, all blood investigations, chest x-
ray, ECG and pap smear were repeated. As a conclusion we found that
Labisia pumila water extract was safe for consumption.
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