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The pharmaceutical industry recognizes the shift to the use of
natural products while also considering the serious concerns that
have arisen regarding the claimed efficacy, quality, and safety of
these products. This volume showcases how pharmaceutical and
nutraceutical compounds from natural products can be used to cure
or prevent diseases. The chapters explore the connections between
agrochemicals and pharmaceuticals and the use of plants and plant
products in the formulation and development of new pharmaceuticals
and nutraceuticals.
Biologically active natural products and their substructures have
long been valuable starting points for medicinal chemistry and drug
discovery. This new volume explores biologically active natural
products and their use in microbial technologies and as
phyto-pharmaceuticals in drug development. It presents detailed
scientific principles and recent research on applications of
nanotechnology in diagnostics and drug delivery. Topics include
pharmacotherapeutically active proteins and peptides; the
biotechnological potential of hydrogen-oxidizing bacteria;
synthesis and production; synthetic colorants, pigments, dyes, and
lakes; and more. The use of various plants is discussed in several
chapters, including Artemisia, Asteraceae, Abutilon indicum,
Prosopis juliflora, Acacia arabica, Aloe barbadensis, Tabermontana
divaricate Linn., among others. With the information presented in
Biologically Active Natural Products: Microbial Technologies and
Phyto-Pharmaceuticals in Drug Development, scientists, faculty, and
graduate students will gain a unique insight into nanotechnology
and natural pharmaceuticals today with practical implementation in
various industrial sectors.
Biologically Active Small Molecules: Modern Applications and
Therapeutic Perspectives focuses on small molecules as active
pharmacological agents, their pharmacotherapeutically active
properties, new approaches in drug discovery using small molecules,
and biopharmaceutic approaches for low molecular weight ligands.
Molecules of low mass play a pivotal role in pharmacology because
they exhibit multifarious pharmacological effects. Small molecules
have become universally popular due to their simple chemistry, easy
separation techniques, versatile acceptance for computational
studies, large number of places for the substitution of active
chemical moieties by well-established synthetic routes with less
effort, better quality attributes, and ability to demonstrate
numerous biological activities. This book provides a
multidisciplinary approach that delivers the most updated knowledge
and advances of some newly developed therapeutically active low
molecular weight compounds. It includes chapters that present
up-to-date and concise content on the classification, structures,
chemical syntheses, medicinal chemistry, pharmacology, biochemical
pathways, mechanism of actions, side effects, and adverse effects
of small molecule drug discovery. The book covers a broad area by
highlighting the advances of inter- and multidisciplinary fields of
medicine, chemical sciences, and pharmaceuticals. The flowcharts,
figures, illustrations, and diagrams provide important information
and will be of great interest for readers.
This volume on applied pharmaceutical science and microbiology
looks at the latest research on the applications of natural
products for drug uses. It focuses on understanding how to apply
the principles of novel green chemistry methods in the vital area
of pharmaceuticals and covers the important aspects of green
microbial technology in the pharmaceutical industry. Chapters
include studies on the applications of natural products used in
folk and regional medicines, such as for digestive problems,
dermatological infections, respiratory diseases, vessel diseases,
diarrhea and dysentery, ringworms, boils, fevers (antipyretic),
skin and blood diseases, mouth sores, channel discharges, and even
cancer. The volume also looks at medical benefit of microbial
fermentation for the conservation of nutrients.
This book highlights recent innovative work in nutraceutical
delivery systems, focusing on strategies and approaches for
delivering maximum health benefits from foods. It presents recent
research-oriented work from diverse global perspectives on
isolation techniques for nutraceutical components, phytosomes,
liposomes, solid dispersions, micelles, self-emulsifying drug
delivery systems, microemulsions, solid lipid nanoparticles,
polyelectrolyte complexes, oral delivery, polymeric nanoparticles,
and more. The book begins with an overview of recent facts and
diverse perspectives on the use of nutraceuticals in medicine and
proceeds to discuss recent techniques in isolation of
nutraceuticals from plants and in solubility enhancement. It looks
at innovations and advances in nanoparticles-based nutraceutical
delivery, such as in solid lipid nanoparticles (SLNs), fabrication
methods of therapeutic nanoparticles, and polymeric
nanoparticles-based nutraceutical delivery system. It also
discusses vesicular delivery systems and biphasic systems for
nutraceutical applications. The book also looks at the challenges
in oral delivery and the latest taste-masking techniques.
Natural Products Chemistry: Biomedical and Pharmaceutical
Phytochemistry focuses on the development of biochemical,
biomedical and their applications. It highlights the importance of
accomplishing an integration of engineering with biology and
medicine to understand and manage the scientific, industrial, and
clinical aspects. It also explains both the basic science and the
applications of biotechnology-derived pharmaceuticals, with special
emphasis on their clinical use. The biological background provided
enables readers to comprehend the major problems in biochemical
engineering and formulate effective solutions. This title also
expands upon current concepts with the latest research and
applications, providing both the breadth and depth researchers
need. The book also introduces the topic of natural products
chemistry with an overview of key concepts. This book is aimed at
professionals from industry, academicians engaged in chemical
science or natural product chemistry research, and graduate-level
students.
This volume presents some of the latest research and applications
in using natural substances and processes for pharmaceutical
products. It presents an in-depth examination of the chemical and
biological properties of selected natural products that are either
currently used or have the potential for useful applications in the
chemical and pharmaceutical industries. It covers emerging
technologies and case studies and is a source of up-to-date
information on the topical subject of natural products and
microbial technology. It provides an applied overview of the field,
from traditional medicinal targets to cutting-edge molecular
techniques. Natural products have always been of key importance to
drug discovery, but as modern techniques and technologies have
allowed researchers to identify, isolate, extract, and synthesize
their active compounds in new ways, they are once again coming to
the forefront of drug discovery.
Medicinal chemistry and pharmacology are closely associated fields,
and the use of natural products for their medicinal properties is
ever-growing. The study of drugs from natural products and their
effects on the living body are explored in this volume. The book
looks into the research, discovery, and characterization of
chemicals that exhibit biological effects. Providing an informative
compilation of research, valuable case studies, and reviews of
existing literature in the area, the book focuses on the
ethnobotanical uses of natural products and phytochemicals for
health care, including applications for diabetes, ulcers, wound
healing, chronic alcoholism, hemorrhoidal treatment, cancer
mitigation, pain management, immunotherapy, and more.
This volume on applied pharmaceutical science and microbiology
looks at the latest research on the applications of natural
products for drug uses. It focuses on understanding how to apply
the principles of novel green chemistry methods in the vital area
of pharmaceuticals and covers the important aspects of green
microbial technology in the pharmaceutical industry. Chapters
include studies on the applications of natural products used in
folk and regional medicines, such as for digestive problems,
dermatological infections, respiratory diseases, vessel diseases,
diarrhea and dysentery, ringworms, boils, fevers (antipyretic),
skin and blood diseases, mouth sores, channel discharges, and even
cancer. The volume also looks at medical benefit of microbial
fermentation for the conservation of nutrients.
Biologically active natural products and their substructures have
long been valuable starting points for medicinal chemistry and drug
discovery. This new volume explores biologically active natural
products and their use in microbial technologies and as
phyto-pharmaceuticals in drug development. It presents detailed
scientific principles and recent research on applications of
nanotechnology in diagnostics and drug delivery. Topics include
pharmacotherapeutically active proteins and peptides; the
biotechnological potential of hydrogen-oxidizing bacteria;
synthesis and production; synthetic colorants, pigments, dyes, and
lakes; and more. The use of various plants is discussed in several
chapters, including Artemisia, Asteraceae, Abutilon indicum,
Prosopis juliflora, Acacia arabica, Aloe barbadensis, Tabermontana
divaricate Linn., among others. With the information presented in
Biologically Active Natural Products: Microbial Technologies and
Phyto-Pharmaceuticals in Drug Development, scientists, faculty, and
graduate students will gain a unique insight into nanotechnology
and natural pharmaceuticals today with practical implementation in
various industrial sectors.
Natural Products Chemistry: Biomedical and Pharmaceutical
Phytochemistry focuses on the development of biochemical,
biomedical and their applications. It highlights the importance of
accomplishing an integration of engineering with biology and
medicine to understand and manage the scientific, industrial, and
clinical aspects. It also explains both the basic science and the
applications of biotechnology-derived pharmaceuticals, with special
emphasis on their clinical use. The biological background provided
enables readers to comprehend the major problems in biochemical
engineering and formulate effective solutions. This title also
expands upon current concepts with the latest research and
applications, providing both the breadth and depth researchers
need. The book also introduces the topic of natural products
chemistry with an overview of key concepts. This book is aimed at
professionals from industry, academicians engaged in chemical
science or natural product chemistry research, and graduate-level
students.
Biochemistry, Biophysics, and Molecular Chemistry: Applied Research
and Interactions provides the background needed in biophysics and
molecular chemistry and offers a great deal of advanced biophysical
knowledge. It emphasizes the growing interrelatedness of molecular
chemistry and biochemistry, and acquaints one with experimental
methods of both disciplines. This book addresses some of the
enormous advances in biochemistry, particularly in the areas of
structural biology and bioinformatics, by providing a solid
biochemical foundation that is rooted in chemistry. Topics include
scientific integrity and ethics in the field; clinical
translational research in cancer, diabetes, and cardiovascular
disease; emerging drugs to treat neurodegenerative diseases; swine,
avian, and human flu; the use of big data in artificial knowledge
in the field; bioinformatic insights on molecular chemistry; and
much more.
This volume focuses on novel therapeutics and strategies for the
development of pharmaceutical products, keeping the drug molecule
as the central component. It discusses current theoretical and
practical aspects of pharmaceuticals for the discovery and
development of novel therapeutics for health problems. Explaining
the necessary features essential for pharmacological activity, it
takes an interdisciplinary approach by including a unique
combination of pharmacy, chemistry, and medicine along with
clinical aspects. It takes into consideration the therapeutic
regulations of the USP along with all the latest therapeutic
guidelines put forward by WHO, and the US Food and Drug
Administration.
This volume focuses on novel therapeutics and strategies for the
development of pharmaceutical products, keeping the drug molecule
as the central component. It discusses current theoretical and
practical aspects of pharmaceuticals for the discovery and
development of novel therapeutics for health problems. Explaining
the necessary features essential for pharmacological activity, it
takes an interdisciplinary approach by including a unique
combination of pharmacy, chemistry, and medicine along with
clinical aspects. It takes into consideration the therapeutic
regulations of the USP along with all the latest therapeutic
guidelines put forward by WHO, and the US Food and Drug
Administration.
The pharmaceutical industry recognizes the shift to the use of
natural products while also considering the serious concerns that
have arisen regarding the claimed efficacy, quality, and safety of
these products. This volume showcases how pharmaceutical and
nutraceutical compounds from natural products can be used to cure
or prevent diseases. The chapters explore the connections between
agrochemicals and pharmaceuticals and the use of plants and plant
products in the formulation and development of new pharmaceuticals
and nutraceuticals.
This valuable new book, Handbook of Research on Medicinal
Chemistry: Innovations and Methodologies, presents some of the
latest advancements in the various fields of combinatorial
chemistry, drug discovery, biochemical aspects, pharmacology of
medicinal agents, current practical problems, and nutraceuticals.
The editors keep the drug molecule as the central component of the
volume and aim to explain the associated features essential to
exhibiting pharmacological activity. With a unique combination of
chapters in biology, clinical aspects, biochemistry, synthetic
chemistry, medicine and technology, the volume provides broad
exposure to the essential aspect of pharmaceuticals. The volume
many important aspects of medicinal chemistry, including techniques
in drug discovery pharmacological aspects of natural products
chemical mediators: druggable targets advances in medicinal
chemistry The field of medicinal chemistry is growing at an
unprecedented pace, and this volume takes an interdisciplinary
approach, covering a range of new research and new practices in the
field. The volume takes into account the latest therapeutic
guidelines put forward by the World Health Organization and the U.S
Food and Drug Administration.. Topics include: drug design drug
discovery natural products and supplements and nutraceuticals
pharmaceutical approaches to sexual dysfunction drug resistance
parasites new natural compounds and identification of new targets
stereochemistry aspects in medicinal chemistry common drug
interactions in daily practices Handbook of Research on Medicinal
Chemistry: Innovations and Methodologies will be a valuable
addition to the bookshelves of pharmaceutical scientists and
faculty as well as for industry professionals.
Biochemistry, Biophysics, and Molecular Chemistry: Applied Research
and Interactions provides the background needed in biophysics and
molecular chemistry and offers a great deal of advanced biophysical
knowledge. It emphasizes the growing interrelatedness of molecular
chemistry and biochemistry, and acquaints one with experimental
methods of both disciplines. This book addresses some of the
enormous advances in biochemistry, particularly in the areas of
structural biology and bioinformatics, by providing a solid
biochemical foundation that is rooted in chemistry. Topics include
scientific integrity and ethics in the field; clinical
translational research in cancer, diabetes, and cardiovascular
disease; emerging drugs to treat neurodegenerative diseases; swine,
avian, and human flu; the use of big data in artificial knowledge
in the field; bioinformatic insights on molecular chemistry; and
much more.
This valuable new book, Handbook of Research on Medicinal
Chemistry: Innovations and Methodologies, presents some of the
latest advancements in the various fields of combinatorial
chemistry, drug discovery, biochemical aspects, pharmacology of
medicinal agents, current practical problems, and nutraceuticals.
The editors keep the drug molecule as the central component of the
volume and aim to explain the associated features essential to
exhibiting pharmacological activity. With a unique combination of
chapters in biology, clinical aspects, biochemistry, synthetic
chemistry, medicine and technology, the volume provides broad
exposure to the essential aspect of pharmaceuticals. The volume
many important aspects of medicinal chemistry, including techniques
in drug discovery pharmacological aspects of natural products
chemical mediators: druggable targets advances in medicinal
chemistry The field of medicinal chemistry is growing at an
unprecedented pace, and this volume takes an interdisciplinary
approach, covering a range of new research and new practices in the
field. The volume takes into account the latest therapeutic
guidelines put forward by the World Health Organization and the U.S
Food and Drug Administration.. Topics include: drug design drug
discovery natural products and supplements and nutraceuticals
pharmaceutical approaches to sexual dysfunction drug resistance
parasites new natural compounds and identification of new targets
stereochemistry aspects in medicinal chemistry common drug
interactions in daily practices Handbook of Research on Medicinal
Chemistry: Innovations and Methodologies will be a valuable
addition to the bookshelves of pharmaceutical scientists and
faculty as well as for industry professionals.
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Michael Buble
CD
(1)
R487
Discovery Miles 4 870
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