The current anti-cancer synthetic medicines are inefficient and unsafe. The plants-based lead molecules such as taxol, camptothecin, podophyllotoxins, vinblastine, vincristine, homoharringtonine and numerous other anticancer compounds from Nature’s arsenal are potentially safe and powerful alternative means that effectively fight against cancer. The volume looks at a variety of medicinal plants and approaches that have beneficial results against cancer. Topics include Unani approaches of anticancer plants, genetic engineering and CRISPR/CAS-mediated editing to enhance anticancer potential, computational approaches used in anticancer plants, and more. The volume also examines the metabolomics of plants that give them anti-cancer properties. This volume, Plant-Derived Anticancer Drugs in the OMICS Era: Biosynthesis, Function, and Applications, will be valuable to cancer researchers and drug developers among others.

Herbal medicines play a critical role in the prevention and treatment of cancer disorders, which are a foremost cause of human disease and death worldwide. This new volume provides a wealth of valuable information on the most vital plant genera and species that have potent anticancer activities, namely Garcinia indica, Centella asiatica Linn, Nigella sativa, Ocimum sanctum, Boswellia serrata Roxb, Catharanthus roseus, Withania somnifera (Linn.) Dunal, Camptotheca acuminata Decne, Taxus baccata L., Panax ginseng, Tinospora cordifolia (Wild) Miers, Taxus brevifolia, and Glycyrrhiza glabra. These anticancer medicinal plants are bestowed with a novel and essential array of chemotherapeutic complexes, biologically active molecules, and secondary metabolites (such as taxol, vinblastine, vincristine, camptothecin, topotecan, etc.) with promising properties to cure cancer in humans. These plants show a vast potential for new drug discovery in the era of modern medicine to fight against cancer. Key features of the book: Provides knowledge of secondary metabolite profiling, active ingredients, modes of action, and pharmacological outcomes of various anticancer plants Discusses the potential of important anticancer plants at the global level Offers information to promote the discovery of new drugs from anticancer plants This book will be valuable to oncologists, cancer researchers, biotechnologists, medicinal chemists, pharmacists, pharmacologists, phytochemists, members of biomedical and pharmaceutical sciences working in the areas of cancer treatment, and upper-level students and residents in pharmacy and medicine.

With the increase in global climate change and challenges to agriculture, this book will be valuable gem for understanding the regulatory networks of stress responsive genes and miRNome. Companies working on engineered plants can take a cue from this book for designing of climate resilient crops. The book will prove as an important chaperon for postgraduate students, teachers, and plant science researchers, scientists in academia and private sector and industries. No such book with compiled knowledge on stress associated microRNAs is available. The book will prove as an important for University and College teachers, and plant science researchers, biotechnologists, bioinformaticians, biochemists, scientists in academia and private sectors.

This volume takes an in-depth look at the potential pharmacological applications of 11 important antidiabetic plants, examining their antihyperglycemic, hypoglycemic, and anti-lipidemic properties along with current genome editing research perspectives. Plant natural products, or phytoconstituents, are promising candidates for antidiabetic pharmacological actions. The phytoconstituents, such as i' avonoids, terpenoids, saponins, carotenoids, alkaloids and glycosides, play vital roles in the current and future potent antidiabetic drug development programs Each chapter reviews a particular plant with antidiabetic properties, explaining the therapeutic aspects, its active antidiabetic compounds, and relevant genome editing technology. The specific plants discussed include Azadirachta indica (commonly known as neem, nimtree or Indian lilac), Gymnema sylvestre (commonly called gymnema, Australian cowplant, and Periploca of the woods), Syzygium cumini (commonly known as Malabar plum, Java plum, black plum, jamun or jambolana), Ceylon cinnamon (or true cinnamon, as opposed to cassia cinnamon), insulin plant (or Costus pictus), Trigonella foenum-graecum (better known as fenugreek), Mulberry, Nigella sativa L. (black caraway, also known as black cumin, nigella, kalojeera, kalonji or kalanji), Aegle marmelos (L.) (commonly known as bael (or bili or bhel), also Bengal quince, golden apple, Japanese bitter orange, stone apple or wood apple), Ficus benghalensis (the banyan, banyan fig and Indian banyan), and of course, garlic (Allium sativum). Antidiabetic Plants for Drug Discovery: Pharmacology, Secondary Metabolite Profiling, and Ingredients with Insulin Mimetic Activity will serve as a valuable source of information for students, drug researchers, medical practitioners, diabetic patients, and many others in the effort to gain understand of how these plant drug molecules can help fight diabetes.

The book provides an informative overview of diabetes mellitus in conjunction with current plant-based treatments for this disease and available methods for studying the antidiabetic activities of scientifically developed plant products, mechanisms of action, their therapeutic superiority, and current genome editing research perspectives and biotechnological approaches. The book begins with an introduction to diabetes, giving an overview of the history, diagnosis, classification, pathophysiology, and risk factors. It goes on to review traditional uses of plants for diabetes along with some ethnobotanical information as well. The results of scientific studies on the various modes of action of antidiabetic plants are discussed, such as the molecular aspects active plant-based antidiabetic drug molecules. A section featuring recent biotechnological advancements of antidiabetic plants and plant-based antidiabetic drugs covers advances in molecular breeding and application of molecular markers, biotechnologically engineered transgenic medicinal plants, and advances in genomic editing tools and techniques. This volume will be helpful for researchers, medical practitioners, academicians, students in the study of plant-based treatments for the treatment of diabetes mellitus.

Provides knowledge on mushrooms as nutraceuticals and functional foods. It will benefit both the direct and indirect audiences. Reviews the health benefit of mushrooms. It is the only vegetarian source of Vitamin D and mushroom industry. If cultivator understand the health benefits, they can cultivate them accordingly. Doctors can recommend these to patients.