This monograph has arisen from the multidisciplinary research extending over biology, robotics and hybrid systems theory. It is inspired by modeling reactive behavior of the immune system cell population, where each cell is considered an independent agent. The authors formulate the optimal control of maximizing the probability of robotic presence in a given region and discuss the application of the Minimum Principle for partial differential equations to this problem.

This monograph has arisen from the multidisciplinary research extending over biology, robotics and hybrid systems theory. It is inspired by modeling reactive behavior of the immune system cell population, where each cell is considered an independent agent. The authors formulate the optimal control of maximizing the probability of robotic presence in a given region and discuss the application of the Minimum Principle for partial differential equations to this problem.