This updated and revised third edition of INTRODUCTION TO MOLECULAR MEDICINE explains the fundamental principles vital to an understanding of the human genome, gene regulation and expression, and genetic engineering. Principles are then applied to the diagnosis and treatment of human disease in infectious diseases, inherited genetic diseases, the immune system and blood cells, cancer, and public health. Fully rewritten and with dozens of new illustrations, the Third Edition presents the basics of molecular biology and its impact on medicine in a concise, conversational format. Each chapter begins with an overview and ends with a summary. This edition also contains new discussions on the human genome project and genetic engineering with updated genetic maps. Ross' Introduction to Molecular Medicine remains a must-have information source for all physicians, residents, and medical students, as the book's stellar reviews demonstrate: "Well written and...presented in a style that is eminently readable...as an introduction to the applications of molecular biology and clinical medicine, Dr. Ross' book is recommended...of particular interest to pathology and clinical medicine residents." --ARCHIVES OF PATHOLOGY on the Second Edition. "will appeal to students and clinicians who will appreciate an introduction to this complicated field which unlike others, is easy and good fun to read." -- Annals of Oncology.

Scientists now understand that cancer is a genetic disease and cutting -edge molecular therapies are making their way from the laboratory into clinical practice. Introduction to Oncogenes and Molecular Cancer Medicine provides the physician with a solid understanding of molecular biology and its applications for the diagnosis and treatment of cancer. The book reviews the basic molecular principles and the basic principles of cancer medicine, including controls of cell growth and senescence, carcinogenesis, tumorogenesis, and epidemiology. The second part of the book gives clinical examples to demonstrate the basic science principles, including chapters on leukemia, colon cancer, and breast cancer. A chapter on molecular diagnostics and screening plus a chapter on new molecular anti-cancer therapies give the reader a look at current cutting-edge therapies as well as as the future of molecular cancer medicine. A useful glossary defines new terminology at-a-glance. Introduction to Oncogenes and Molecular Cancer Medicine is for all physicians seeking a better understanding of the modern molecular principles of cancer medicine. Written in a user-friendly, conversational format, this text will be welcomed by all physicians eager to sharpen their own understanding of molecular cancer medicine as well as to help them provide patients with balanced information on the advances and limitations of current treatment options.

Ecco finalmente disponibile in italiano un testo che sin dalla sua prima edizione, nel 1992, si A] rivelato una (TM)indispensabile guida per la comprensione di una scienza giovane dai rapidi e promettenti sviluppi. Introduzione alla Medicina Molecolare, giunto oggi a una terza edizione completamente rinnovata, presenta in modo sintetico ma esauriente i principi scientifici e tecnologici di questa disciplina e fornisce, con un linguaggio ampiamente accessibile, gli strumenti concettuali di base per comprendere

a [ il genoma umano

a [ la (TM)espressione e la regolazione genica

a [ i diversi aspetti della (TM)ingegneria genetica che consentono la manipolazione del DNA

a [ la clonazione umana.

Vengono quindi proposte le applicazioni delle tecnologie molecolari nella (TM)ambito della diagnostica e della terapia delle malattie infettive, delle patologie genetiche ereditarie, della (TM)ematologia e della (TM)oncologia. Disegni e tabelle favoriscono la comprensione dei diversi argomenti, che vengono riassunti al termine di ogni capitolo per consentirne una corretta interpretazione. Il testo sarA un prezioso strumento per studenti, tecnici, medici e specializzandi e consentirA loro di seguire la (TM)evoluzione e comprendere i progressi della medicina molecolare.