Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis. However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds. Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management. Biofilms and their associated complications have been found to be involved in up to 80% of all infections. A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind. These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to 'cure' the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine. This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations. The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management. Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.

Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis. However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds. Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management. Biofilms and their associated complications have been found to be involved in up to 80% of all infections. A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind. These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to 'cure' the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine. This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations. The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management. Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.

In Clinical Equine Oncology, Derek Knottenbelt will add to his very well-regarded range of equine titles for Elsevier by producing an oncology book that, like his recently published Pascoe's Principles & Practice of Equine Dermatology 2e, will have several distinguishing features that will make it of the widest possible appeal. The design and practical features of the dermatology book can and should be applied to the present proposal; together they can be viewed as companion texts. More than 50 different types of tumor are covered, including tumors that occur in each of the 10 body systems. Over 800 excellent-quality photographs show the appearance of pathologies and cancerous conditions both before and after treatment. More than 80 full-color diagrams summarize key information. Detailed Pathology section describes common neoplasms in horses, cites research literature, and describes what is generally known about each condition. Authoritative, inclusive, and unique coverage is likely to remain the standard reference for years to come. Expert authors are recognized as the top experts in the field of equine oncology. Practical, colorful design includes icon-based references for quick appraisal of prevalence and prognosis.

This is an indispensable reference for equine veterinary practitioners, veterinary students, and others involved in breeding and keeping horses. This new edition has been fully revised, updated and re-written in a more user-friendly style and format with the inclusion of high quality line drawings and photographs to aid understanding. Also, a conscious decision was made to use generic drug names making this as relevant as possible for everybody working in the equine field all over the world. A listing of haematological, biochemical, physiological, and therapeutic data is contained in just one volume, designed with the final-year vet student and recent graduate in mind. Information on drug dosages and adverse reactions reflects manufacturers' recommendations in data sheets and literature inserts. Clinical Aids section provides highly practical advice and quick synopses for the most common scenarios likely to occur on a field visit, such as bandaging techniques, humane destruction, and restraint techniques. Practical, universal relevance is created by the use of SI units and generic drug names - making this reference useful to everyone working in the equine field all over the world, whether vet student or equine specialist. Practical, step-by-step instructions summarize principal diagnostic tests. NEW! A handy interactive app format allows extra-quick, point-of-care reference. NEW! A full-colour design includes more high-quality line drawings and adds photographs showing nerve block techniques. NEW! Revised clinical techniques section deals with the difficult horse and restraint methods, including field anaesthesia. NEW algorithmic approach updates and clarifies emergency procedures, wound management, disease control protocols, and more. NEW! Wound dressings and suturing sections are thoroughly modernized.