Meta-analysis, decision analysis, and cost-effectiveness analysis are the cornerstones of evidence-based medicine. These related quantitative methods have become essential tools in the formulation of clinical and public policy based on the synthesis of evidence. All three methods are taught with increasing frequency in medical schools and schools of public health and in health policy courses at the undergraduate and graduate level. This book is a lucid introduction, and will serve the needs of students taking introductory courses that cover these topics. It will also be useful to clinicians and policymakers who need to understand the quantitative underpinnings of the methods in order to best apply the information that derives from them. The second edition of this popular book adds new material on cumulative meta-analysis as a method to explore heterogeneity. The coverage of cost-effectiveness analysis has been brought into close alignment with recommendations of the U.S. Public Health Panel on Cost-Effectiveness Analysis in Health and Medicine. Many of the examples have been replaced with more current examples, and all of the material has been updated to reflect recent advances in the methods and the emergence of consensus about some previously controversial issues. analysis. These three closely related methods have become even more important for synthesizing research since the first edition was published in 1994. And they have gained legitimacy as tools for guiding health policy. In the Second Edition, Petitti has added new material on cumlative meta-analysis and the exploration of heterogeneity, incorporated recommendations for standardizing the conduct of cost-effectiveness analysis, and updated the rest of the text.

This text focuses on areas of public health practice in which the systematic application of epidemiologic methods can have a large and positive impact. It describes how best to apply traditional epidemiologic methods for determining disease etiology to "real-life" problems in public health and health services research. Brownson and Petitti's much-needed book bridges the gap between theoretical epidemiology and public health practice, and covers a number of topics not addressed by other epidemiology texts with a focus on methods. This second edition contains a new chapter on the development and use of systematic reviews and one on epidemiology and the law. Each chapter includes one or more case studies intended to illustrate major points from the chapter and to provide a basis for teaching exercises. All of the chapters are authored by leading experts in the fields of epidemiology and public health, and all are fully revised and updated.
The book is intended for practitioners in epidemiology as well as for students in epidemiology and related disciplines that rely on epidemiologic methods and reasoning. It is a practical and informative book for use in academic institutions, federal agencies which have significant educational missions, state and local public health agencies, and health care organizations. By providing a resource of immense accessibility to several key audiences, this edition of Applied Epidemiology: Theory to Practice further extends the fields ability to make a real difference on behalf of better health for all.