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Our understanding of human evolution is proceeding at an unprecedented rate over the last years due to spectacular fossil finds, reconstructions based on genome comparison, ancient DNA sequencing and new insights into developmental genetics. This book takes an integrative approach in which the development of the human embryo, the evolutionary history of our body, the structure of human populations, their dispersal over the world and their cultures are examined by integrating paleoanthropology, developmental biology, comparative zoology, population genetics and phylogenetic reconstruction. The authors discuss questions like: - What do we know about ancient humans? - What happens in the development of an embryo? - How did we manage to walk upright and why did we lose our hair? - What is the relationship between language, migration and evolution? - How does our body respond to the challenges of modern society? In addition to being a core text for the study of the life sciences, Human Evolution and Development is an easy-to-read overview for the interested layperson.
The genomics revolution has expanded from its origins in molecular biology to impact upon every discipline in the life sciences, including ecology. Several lines of ecological research can now be profitably addressed using genomics technology, including issues of nutrient cycling, population structure, life-history variation, trophic interaction, stress responses, and adaptation to environmental change. This new edition addresses a series of fundamental ecological questions: the relationship between community structure and ecological function in ecosystems; how variation in life-history patterns among species can be explained from interaction between the genome and the environment; the molecular responses to changing and toxic environmental conditions; adaptive phenotypes and their relationship to genetic variation. Each of these questions is evaluated in the light of recent advances in genomics research, paying particular attention to data obtained from sequencing and screening of environmental genomes (metagenomics), microarray-based transcription profiling, gene expression directed by signal-transduction pathways, and the analysis of genomic polymorphisms. The chapters covering these key areas are preceded by discussions of genomics methodology (including an overview of next-generation sequencing technologies) and comparative genomics, and the book concludes with a chapter on integrative approaches such as ecological control analysis. The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models. An Introduction to Ecological Genomics incorporates a balance of plant, animal, and microbial examples, and continues to define the new and exciting field of ecological genomics.
The genomics revolution has expanded from its origins in molecular biology to impact upon every discipline in the life sciences, including ecology. Several lines of ecological research can now be profitably addressed using genomics technology, including issues of nutrient cycling, population structure, life-history variation, trophic interaction, stress responses, and adaptation to environmental change. This new edition addresses a series of fundamental ecological questions: the relationship between community structure and ecological function in ecosystems; how variation in life-history patterns among species can be explained from interaction between the genome and the environment; the molecular responses to changing and toxic environmental conditions; adaptive phenotypes and their relationship to genetic variation. Each of these questions is evaluated in the light of recent advances in genomics research, paying particular attention to data obtained from sequencing and screening of environmental genomes (metagenomics), microarray-based transcription profiling, gene expression directed by signal-transduction pathways, and the analysis of genomic polymorphisms. The chapters covering these key areas are preceded by discussions of genomics methodology (including an overview of next-generation sequencing technologies) and comparative genomics, and the book concludes with a chapter on integrative approaches such as ecological control analysis. The authors also provide a comparative survey of the properties of genomes (genome size, gene families, synteny, and polymorphism) for prokaryotes as well as the main eukaryotic models. An Introduction to Ecological Genomics incorporates a balance of plant, animal, and microbial examples, and continues to define the new and exciting field of ecological genomics.
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