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The Second International Symposium on "The Influence of Antibiotics
on the Host Parasite Relationship" was held in Munich, F. R. G. ,
from March 28 to 30,1985. The topics of the meeting dealt with the
aspects of changes in bacterial metabolism and structure which
occur under the influence of antibiotics, and with the effects of
such changes on the antibacterial host resistance. The influence on
pathogenicity factors, changes in the outer membrane of bacteria,
as well as the influence on the individual components of the
defence system were analysed in detail. In addition, these studies
showed that antibiotics proved to be an excellent tool for the
examination of bacterial physiology, so that, 50 years after the
introduction of antibiotics, additional important knowledge can be
gained about the effect of these substances on bacteria.
Considering the observations reported, it appears justifiable to
postulate that new antibiotics should be routinely tested with
respect to their possible effects on antiinfectious resistance. Of
course, a consensus will have to be found on which to base methods
and criteria employEUROd. The symposium documented an increasing
interest of microbiologists and clini cians for this field of
research. It would not have been possible to organize it without
the substantial support of the Paul Ehrlich Society as well as of
Squibb-Von Heyden Pharma, Inc. Particular help concerning the
organization has been given by Werner Kremer of Squibb-Von Heyden
Pharma.
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