Intended for specialists in B cell immunology, this is an investigation of such topics as the movement of a monoclonal antibody from the laboratory into the clinic, the field of Fc receptors, the impact of monoclonal antibodies on the diagnosis and treatment of human cancer, and detailed analyses of specific antibody systems: mouse lambda and human kappa. Antibodies have always been vital to any major progress within immunology. From diagnostic tools to vehicles for modern therapy against cancer, infections, and autoimmune diseases, antibodies serve many purposes, yet our knowledge of them, their properties and structural characteristics is incomplete. "The Antibodies" series seeks to provide the scientific community with a platform for a comprehensive review of topics of contemporary interest for specialists in this area.