Analysis by In Situ Hybridization of Cytokine mRNAS Expression in Thymic Nurse Cells.- Genetic Expression of the C-CBL Proto-Oncogene in Human Thymocytes.- Production and Selection of B Lymphocytes in Bone Marrow: Lymphostromal Interactions and Apoptosis in Normal, Mutant and Transgenic Mice.- Thymic Neuroendocrine Self Peptides and T Cell Selection.- Human Fetal Liver Cells Differentiate into Thymocytes in Chimeric Mouse Fetal Thymus Organ Culture.- Towards Identification of Memory B Cells in Human Tonsils.- Prolonged IL-4 Treatment Decreases the TNP-Specific Memory Formation for IgG1.- Selection of Anti-Arsonate Idiotype (CRIA) in A/J Mice by the Immune Network.- The Life History and Functional Roles of Accessory Cells.- The Role of Macrophages in Regeneration of Splenic Tissue after Autologous Transplantation in Rat.- In Vivo Antigen Presentation Capacity of Dendritic Cells from Oral Mucosa and Skin Draining Lymph Nodes.- Liposome Mediated Modulation of Macrophage Functions.- In Vivo gp39-CD40 Interactions Occur in the Non-Follicular Compartments of the Spleen and Are Essential for Thymus Dependent Antibody Responses and Germinal Center Formation.- The Role of Dendritic Cells in the Uptake and Presentation of Oral Antigens.- Blockage of Thymic Medullary Epithelial Cell Activation: In Vivo Consequences.- Half-Lives of Antigen/MHC Class II Complexes Differ between Distinct Organ Microenvironments.- Regulation of Neural and Peripheral Cytokine Production by Benzodiazepines and Endogenous Anxiogenic Peptides.- Could ACTH be of Prime Importance in Rapidly Altering the Thymocyte Composition in the Thymus?.- Adrenergic and Cholinergic Regulation of Apoptosis and Differentiation of Thymic Lymphocytes.- Autoimmune lpr and gld Mice: Models of Abnormal Adhesion Molecule Regulation and Defective Lymphocyte Traffic.- Vascular Addressin Expression in Peyer's Patches: An in Vivo Study of Site-Associated Regulation.- Domain 5 of the Intercellular Adhesion Molecule-1 (ICAM-1) Is Involved in Adhesion of B-Cells and Follicular Dendritic Cells.- Modifications of the Expression of Homing and Adhesion Molecules in Infiltrated Islets of Langerhans in Nod Mice.- Characterization of Giant Perivascular Spaces in the Thymus of the Nonobese Diabetic Mouse.- Adhesion Molecule PECAM-1/CD31 Is Expressed on Defined Subsets of Murine LAK Cells.- Intrathymic Gap Junction-Mediated Communication.- Complement and Antibody Enhance Binding and Uptake of HIV-1 by Bone Marrow Cells.- Follicular Dendritic Cells (FDC) Are Not Productively Infected with HIV-1 in Vivo.- Lymph Node Pathology in Experimental FIV Infection.- Lymphocyte Lifespan in Murine Retrovirus-Induced Immunodeficiency.- Analysis of HIV Infections in Human Macrophage-Like Cell Lines.- The Pivotal Role of the Immunoglobulin Receptor of Tumor Cells from B Cell Lymphomas of Mucosa Associated Lymphoid Tissue (MALT).- TNF?- Is Involved in the Mechanism of Murine Thymic Lymphoma Prevention by Bone Marrow Grafting.- Analysis of Germinal Centres in the Immune Response to Oxazolone.- Cytokine Responsiveness of Germinal Center B Cells.- The Differences in Survival and Phenotype between Centroblasts and Centrocytes.- In Vivo Localisation Patterns and Cell-Cell Interactions of Cytokine Producing T-Cells and Specific Antibody Forming B-Cells.- DHEAS Enhances Germinal Center Responses in Old Mice.- Cellular Origin of Follicular Dendritic Cells.- Germinal Centers Develop at Predilicted Sites in the Chicken Spleen.- Expression and Function of DRC-1 Antigen.- The Appendix Functions as a Mammalian Bursal Equivalent in the Developing Rabbit.- Development of Components of the Mucosal Immune System in SCID Recipient Mice.- Many Newly Formed T Lymphocytes Leave the Small Intestinal Mucosa via Lymphatics.- Analysis of IgA-Producing Hybridomas Derived from Peritoneal Bl Cells.- Modulation of the Neonatal IgA Response to Enteric Antigens by Maternal Antibody.- Antibody-Forming Cells (AFCs) in the Lung Lymphoid Tissue afte...

The 11th International Conference on Lymphoid Tissues and Immune Reactions was held in Spa-Liege (Belgium), from 4 to 8 July 1993. The regular devotees refer to these conferences as the "Germinal Centre Conferences or GCC". In the 1960s, the germinal centres were the subject of such considerable study and speculation that a group of dynamic people decided to devote an international conference centered on that topic. This led to the fIrst GCC organized in Bern in 1966. Following the success of this initial meeting, further sessions have been organized at regular intervals and, over the years, the scope of the GCC has been broadened. Nowadays, the GCC conferences are dedicated to in vivo immunology and deal mainly with cellular, functional and molecular aspects of the lymphoid system. The credo of these conferences is "in vivo veritas," implying that the sole investigation of components (like molecules or cell populations) only gives a partial truth. Ultimately, the components have to be explored in their global context in order to see how they interact with other parts and how they are integrated as a whole to ensure the homeostasis of the immune system. In 1966, the GCC lasted 3 days and included 57 contributions "which were discussed at length. " The present conference lasted 4 days and accommodated 2 honorary lectures, 80 free papers and 209 poster presentations. Out of those presentations, a selection was performed by the Chairpersons to compose the present volume.