The present volume contains the proceedings of the 23rd Mos bach Colloquium on "Protein-Protein Interactions." It includes the paper by Prof. S. LIFSON who unfortunately was unable to attend. Discussions were included whenever possible in order to make the complete proceedings accessible to the future reader. The colloquium was generously supported by the firms who are corporate members of the Gesellschaft fur Biologische Chemie. Dr. W. B. GRATZER and Dr. L. JAENICKE, as weIl as some of the invited speakers, were a tremendous help in preparing the program and we wish to thank them for their helpfuI suggestions and advice. Our appreciation extends to Prof. E. AUHAGEN and Prof. H. GIBIAN, and their secretaries, who shared the burden of organizing the colloquium. In addition, we wish to express our gratitude to Springer-Ver Iag, and especially to Dr. H. MAYER-KAUPP for editoriaI help and for the rapid publication of this volume. We hope that the reader, Iike the audience in the Mosbach market hall, will gain an impression of the present state of protein research and of the way in which intermolecular interactions hold specific implications for the structure and function of proteins. Regensburg and Wurzburg, autumn 1972 R. JAENICKE E. HELMREICH Contents Introduction. R. JAENICKE (Regensburg) 1 Molecular Forees. S. LIFSON (Rehovot) ................... 3 Structure, Function and Dynamics of a ReguIatory Enzyme: Aspartate Transcarbamylase. H. K. SCHACHMAN (Berkeley) 17 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 . . . . . . . . . . . . . ."

This is a comprehensive study of one of the most startling examples of dollar diplomacy--the effort of the United States and the United Kingdom to monopolize the free world's supply of uranium and thorium during and immediately following World War II. Originally published in 1986. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

This is a comprehensive study of one of the most startling examples of dollar diplomacy--the effort of the United States and the United Kingdom to monopolize the free world's supply of uranium and thorium during and immediately following World War II.

Originally published in 1986.

The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These paperback editions preserve the original texts of these important books while presenting them in durable paperback editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

es gibt deren an hundert - zu schildern. Zahlreiche Methoden habe ich selbst ausprobiert und glaube, fiir wissenschaftliche Zwecke die Makro methode nach WESTERGREN in erster Linie empfehlen zu diirfen. Fiir praktische Zwecke habe ich selbst einen kleineren Senkungsapparat an gegeben, der sich zu Makro- und Mikrobestimmung gleich gut eignet. Bei der Darstellung der Bedeutung der Erythrocytensenkung fiir die innere Medizin stiitze ich mich vor allem auf eigene Erfahrungen und habe als Belege aus dem groBen Material der KIinik nur wenige Fane ausgewahlt, bei denen dio senkungsbeeinflussenden Faktoren einwandfrei klargestellt werden konnten. lch war bemiiht zu zeigen, daB Senkungsbeschleunigung in erster Linie ein MafJ der Resorption entziindlicher oder nekrotischer Produkte ist und mithin auch ein MaB der Ausdehnung einer Entziindung. Dadurch gewinnt die Senkung an diagnostischem und prognostischem Werte bei Erkrankungen, bei denen das Vorhandensein oder die Ausdehnung ent ziindlicher oder nekrotischer Herde sonst schwer erkennbar und der Verlauf der Erkrankung mit anderen klinischen Methoden nicht so gut verfolgbar ist. So konnte ich auch auf mehrere neue Gesichtspunkte aufmerksam machen, wie auf die Bedeutung der Senkungsreaktion fiir die BeUJ, 'teilung entziindlichet Herde im Darm bei Typhus, fiir die Diagnose entziindlicher Erkrankungen des Herzens (floride Endokarditis, Myo karditis, Mesaortitis), fiir die Prognose der akuten Glomerulonephritis und anderes. Ferner habe ich die Bedeutung der Senkungsreaktion fiir die Klinik der Coronarthrombose, der Leber- und Gallenblasenerkrankungen, fiir die Differentialdiagnose der Hypertonie, die hisher wenig heachtet wurde, ausfiihrlich dargestellt."

The letters of Levi Bird Duff present a perceptive picture of life in the Army of the Potomac from 1861 to 1864. They are unusual for their literacy, descriptions and continuity, the strength of opinions expressed, and their source: a private who rose to the rank of lieutenant colonel, thus a witness of the army at several levels. Leadership, organizational, weather, and morale problems that plagued Union troops are made clear. Written only for the eyes of Duff's love, the messages reflect the tension experienced by many soldiers between the conflicting calls of duty and affection.