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Glycotechnology brings together in one place important
contributions and up-to-date research results in this fast moving
area. Glycotechnology serves as an excellent reference, providing
insight into some of the most challenging research issues in the
field.
In 1898 Camillo Golgi reported his newly observed intracellular
structure, the apparato reticolare interno, now universally known
as the Golgi Apparatus. The method he used was an ingenious
histological technique (La reazione nera) which brought him fame
for the discovery of neuronal networks and culminated in the award
of the Nobel Prize for Physiology and Medicine in 1906. This
technique, however, was not easily reproducible and led to a
long-lasting controversy about the reality of the Golgi apparatus.
Its identification as a ubiquitous organelle by electron microscopy
turned out to be the breakthrough and incited an enormous wave of
interest in this organelle at the end of the sixties. In recent
years immunochemical techniques and molecular cloning approaches
opened up new avenues and led to an ongoing resurgence of interest.
The role of the Golgi apparatus in modifying, broadening and
refining the structural information conferred by
transcription/translation is now generally accepted but still
incompletely understood. During the coming years, this topic
certainly will remain center stage in the field of cell biology.
The centennial of the discovery of this fascinating organelle
prompted us to edit a new comprehensive book on the Golgi apparatus
whose complexity necessitated the contributions of leading
specialists in this field. This book is aimed at a broad readership
of glycobiologists as well as cell and molecular biologists and may
also be interesting for advanced students of biology and life
sciences.
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