We could start writing this book by saying, with several other authors, that the brain is the most powerful and complex information processing device known, whether naturally developed or created artificially. Although we fully agree with this statement, in doing so we would be misleading the reader, in the sense that the present book basically aims to formalize the knowledge concerning brain physiology accumulated over the past few decades. Instead of merely describing the complexity of the cerebral str- ture or presenting a collection of commentaries and reviews of interesting experimental results, we take into account novel achievements in quantum information and quantum computation, and avail ourselves of recently - veloped mathematical tools. Neuroscience was bom in the 19'~ century with the works of Paul Brocca. However, this fledgling field experienced a boom only in recent times, following the development of powerful non-invasive techniques for probing the neural circuitry supporting the complex cognitive functions of the human brain. Although sophisticated mathematical models and phy- cal theories are the basic tools behind the conceptual foundations and a- lytical implementation of these modem techniques, to the best of our knowledge no effort was made to formalize the actual knowledge about brain function into a coherent theoretical framework incorporating the - cent developments in mathematical and physical science. Addressing this lack was our first motivation in writing this book.

Fuzzy Logic in Action: Applications in Epidemiology and Beyond, co-authored by Eduardo Massad, Neli Ortega, Laecio Barros, and Claudio Struchiner is a remarkable achievement. The book brings a major paradigm shift to medical sciences exploring the use of fuzzy sets in epidemiology and medical diagnosis arena. The volume addresses the most significant topics in the broad areas of epidemiology, mathematical modeling and uncertainty, embodying them within the framework of fuzzy set and dynamic systems theory. Written by leading contributors to the area of epidemiology, medical informatics and mathematics, the book combines a very lucid and authoritative exposition of the fundamentals of fuzzy sets with an insightful use of the fundamentals in the area of epidemiology and diagnosis. The content is clearly illustrated by numerous illustrative examples and several real world applications. Based on their profound knowledge of epidemiology and mathematical modeling, and on their keen understanding of the role played by uncertainty and fuzzy sets, the authors provide insights into the connections between biological phenomena and dynamic systems as a mean to predict, diagnose, and prescribe actions. An example is the use of Bellman-Zadeh fuzzy decision making approach to develop a vaccination strategy to manage measles epidemics in Sao Paulo. The book offers a comprehensive, systematic, fully updated and self- contained treatise of fuzzy sets in epidemiology and diagnosis. Its content covers material of vital interest to students, researchers and practitioners and is suitable both as a textbook and as a reference. The authors present new results of their own in most of the chapters. In doing so, they reflect the trend to view fuzzy sets, probability theory and statistics as an association of complementary and synergetic modeling methodologies.

We could start writing this book by saying, with several other authors, that the brain is the most powerful and complex information processing device known, whether naturally developed or created artificially. Although we fully agree with this statement, in doing so we would be misleading the reader, in the sense that the present book basically aims to formalize the knowledge concerning brain physiology accumulated over the past few decades. Instead of merely describing the complexity of the cerebral str- ture or presenting a collection of commentaries and reviews of interesting experimental results, we take into account novel achievements in quantum information and quantum computation, and avail ourselves of recently - veloped mathematical tools. Neuroscience was bom in the 19'~ century with the works of Paul Brocca. However, this fledgling field experienced a boom only in recent times, following the development of powerful non-invasive techniques for probing the neural circuitry supporting the complex cognitive functions of the human brain. Although sophisticated mathematical models and phy- cal theories are the basic tools behind the conceptual foundations and a- lytical implementation of these modem techniques, to the best of our knowledge no effort was made to formalize the actual knowledge about brain function into a coherent theoretical framework incorporating the - cent developments in mathematical and physical science. Addressing this lack was our first motivation in writing this book.

Fuzzy Logic in Action: Applications in Epidemiology and Beyond, co-authored by Eduardo Massad, Neli Ortega, Laecio Barros, and Claudio Struchiner is a remarkable achievement. The book brings a major paradigm shift to medical sciences exploring the use of fuzzy sets in epidemiology and medical diagnosis arena. The volume addresses the most significant topics in the broad areas of epidemiology, mathematical modeling and uncertainty, embodying them within the framework of fuzzy set and dynamic systems theory. Written by leading contributors to the area of epidemiology, medical informatics and mathematics, the book combines a very lucid and authoritative exposition of the fundamentals of fuzzy sets with an insightful use of the fundamentals in the area of epidemiology and diagnosis. The content is clearly illustrated by numerous illustrative examples and several real world applications. Based on their profound knowledge of epidemiology and mathematical modeling, and on their keen understanding of the role played by uncertainty and fuzzy sets, the authors provide insights into the connections between biological phenomena and dynamic systems as a mean to predict, diagnose, and prescribe actions. An example is the use of Bellman-Zadeh fuzzy decision making approach to develop a vaccination strategy to manage measles epidemics in Sao Paulo. The book offers a comprehensive, systematic, fully updated and self- contained treatise of fuzzy sets in epidemiology and diagnosis. Its content covers material of vital interest to students, researchers and practitioners and is suitable both as a textbook and as a reference. The authors present new results of their own in most of the chapters. In doing so, they reflect the trend to view fuzzy sets, probability theory and statistics as an association of complementary and synergetic modeling methodologies.

Global Health Informatics: How Information Technology Can Change Our Lives in a Globalized World discusses the critical role of information and communication technologies in health practice, health systems management and research in increasingly interconnected societies. In a global interconnected world the old standalone institutional information systems have proved to be inadequate for patient-centered care provided by multiple providers, for the early detection and response to emerging and re-emerging diseases, and to guide population-oriented public health interventions. The book reviews pertinent aspects and successful current experiences related to standards for health information systems; digital systems as a support for decision making, diagnosis and therapy; professional and client education and training; health systems operation; and intergovernmental collaboration.

Mathematical Approaches to Liver Transplantation provides mathematical approaches to the optimization of liver graft distribution. Through mathematical and computational methods, several aspects related to organ allocation are tackled, with possible solutions presented. The book discusses topics such as patient selection for liver transplantation, transplantation procedures, dynamics of organs waiting list, improvement on grafts allocation, live donors and MELD scale. The content focuses on liver transplantation, however the mathematical approaches presented can be successfully replicated to different organs. This book is a valuable source for mathematical biologists, bioinformaticians, and several members of biomedical field who are involved in decision-making related to organs transplantation.