Cognitive function involves the participation of many different neurotransmitter systems in a variety of brain areas. The centerpiece of investigation regarding cognitive function has classically been the cholinergic system, but it has beome increasingly clear that other transmitter systems interact with cholinergic systems to provide the neural basis for cognitive function.

This book brings together cutting edge research to determine how the transmitter interactions form the mechanistic bases for attention, learning and memory. This research on transmitter interactions not only provides a more accurate, though complex, picture of how the brain works to provide cognitive function, it also provides important new levels of understanding about the mechanisms of cognitive dysfunction and novel avenues for therapeutic treatment. The researchers who contributed to this volume both reviewed the latest findings but also point to the directions of advancement of the field of neurotransmitter interactions and cognitive function.

The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans. Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications. The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. It also explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimer's, schizophrenia, and ADHD. Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.

The costs associated with a drug's clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans.

Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications.

The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. Italso explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimer's, schizophrenia, and ADHD.

Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.