This book constitutes the refereed proceedings of the 8th IAPR International Conference on Pattern Recognition in Bioinformatics, PRIB 2014, held in Stockholm, Sweden in August 2014. The 9 revised full papers and 9 revised short papers presented were carefully reviewed and selected from 29 submissions. The focus of the conference was on the latest Research in Pattern Recognition and Computational Intelligence-Based Techniques Applied to Problems in Bioinformatics and Computational Biology.

The ?eld of bioinformatics has two main objectives: the creation and main- nance of biological databases and the analysis of life sciences data in order to unravel the mysteries of biological function. Computer science methods such as patternrecognition,machinelearning,anddatamining haveagreatdealtoo?er the ?eld of bioinformatics. The Pattern Recognition in Bioinformatics (PRIB) meeting was established in 2006 under the auspices of the International Asso- ation of Pattern Recognition (IAPR) to create a focus for the application and development of computer science methods to life science data. The 5th PRIB conference was held in Nijmegen, The Netherlands, on 22-24 September 2010. A total of 46 papers were submitted to the conference for peer review. Of those, 38 (83%) were accepted for publication in these proceedings. The invited speakers were Rita Casadio (Bologna Biocomputing Group, Italy), Florence d'Alch' e-Buc (Universit' e d'Evry-Val d'Essonne, France), Daniel - son (Tu ..bingen University, Germany), and Natasa Przulj (Imperial College L- don, UK). Tutorials weredeliveredby Concettina Guerra (Universit' adi Padova, Italy), Clarisse Dhaenens (Laboratoire LIFL/INRIA, France), Laetitia Jourdan (Laboratoire LIFL/INRIA, France), Neil Lawrence (University of Manchester, UK), and Dick de Ridder (Delft University of Technology).

This book constitutes the refereed proceedings of the 5th European Conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics, EvoBIO 2007, held in Valencia, Spain in April 2007, colocated with the Evo* 2007 events.

The 28 revised full papers were carefully reviewed and selected from 60 submissions. Bringing experts in computer science together with experts in bioinformatics and the biological sciences resulted in contributions on fundamental and theoretical issues, along with a wide variety of papers dealing with different applications areas, such as biomarker discovery, cell simulation and modeling, ecological modeling, fluxomics, gene networks, biotechnology, metabolomics, microarray analysis, phylogenetics, protein interactions, proteomics, sequence analysis and alignment, as well as systems biology

Evolutionary computation (EC) techniques are e?cient nature-inspired pl- ning and optimization methods based on the principles of natural evolution and genetics. Due to their e?ciency and the simple underlying principles, these methods can be used for a large number of problems in the context of problem solving, optimization, andmachinelearning. Alargeandcontinuouslyincreasing number of researchers and practitioners make use of EC techniques in many - plication domains. The book at hand presents a careful selection of relevant EC applications combined with thorough examinations of techniques for a successful application of EC. The presented papers illustrate the current state of the art in the application of EC and should help and inspire researchers and practitioners to develop e?cient EC methods for design and problem solving. All papers in this book were presented during EvoWorkshops 2005, which was a varying collection of workshops on application-oriented aspects of EC. Since 1999, the format of the EvoWorkshops has proved to be very successful and well representative of the advances in the application of EC. Consequently, over the last few years, EvoWorkshops has become one of the major events addressing the application of EC. In contrast to other large conferences in the EC ?eld, the EvoWorkshops focus solely on application aspects of EC and are an important link between EC research and the application of EC in a large variety of di?erent domain

Evolutionary Computation (EC) deals with problem solving, optimization, and machine learning techniques inspired by principles of natural evolution and - netics. Just from this basic de?nition, it is clear that one of the main features of theresearchcommunityinvolvedinthestudyofitstheoryandinitsapplications is multidisciplinarity. For this reason, EC has been able to draw the attention of an ever-increasing number of researchers and practitioners in several ?elds. In its 6-year-long activity, EvoNet, the European Network of Excellence in Evolutionary Computing, has been the natural reference and incubator for that multifaceted community. EvoNet has provided logistic and material support for thosewhowerealreadyinvolvedinECbut, inthe?rstplace, ithashadacritical role in favoring the signi?cant growth of the EC community and its interactions with longer-established ones. The main instrument that has made this possible has been the series of events, ?rst organized in 1998, that have spanned over both theoretical and practical aspects of EC. Ever since 1999, the present format, in which the EvoWorkshops, a collection of workshops on the most application-oriented aspects of EC, act as satellites of a core event, has proven to be very successful and very representative of the multi-disciplinarity of EC. Up to 2003, the core was represented by EuroGP, the main European event dedicated to Genetic Programming. EuroGP has been joined as the main event in 2004 by EvoCOP, formerly part of EvoWorkshops, which has become the European Conference on Evolutionary Computation in Combinatorial Optimizatio

  This book constitutes the joint refereed proceedings of six workshops, EvoWorkshops 2003, held together with EuroGP 2003 in Essex, UK in April 2003. The 63 revised full papers presented were carefully reviewed and selected from a total of 109 submissions. In accordance with the six workshops covered , the papers are organized in topical sections on bioinformatics, combinatorial optimization, image analysis and signal processing, evolutionary music and art, evolutionary robotics, and scheduling and timetabling.

The ?eld of bioinformatics has two main objectives: the creation and main- nance of biological databases, and the discovery of knowledge from life sciences data in order to unravel the mysteries of biological function, leading to new drugs and therapies for human disease. Life sciences data come in the form of biological sequences, structures, pathways, or literature. One major aspect of discovering biological knowledge is to search, predict, or model speci?c infor- tioninagivendatasetinordertogeneratenewinterestingknowledge.Computer science methods such as evolutionary computation, machine learning, and data mining all have a great deal to o?er the ?eld of bioinformatics. The goal of the 6th EuropeanConference on EvolutionaryComputation, Machine Learning, andDataMininginBioinformatics(EvoBIO2008)wastobringtogetherexperts from these ?elds in order to discuss new and novelmethods for tackling complex biological problems. The 6th EvoBIO conference was held in Naples, Italy on March 26-28, 2008 at the "Centro Congressi di Ateneo Federico II." EvoBIO 2008 was held jointly with the 11th European Conference on Genetic Programming (EuroGP 2008), the 8th European Conference on Evolutionary Computation in Combinatorial Optimisation (EvoCOP 2008), and the Evo Workshops. Collectively, the conf- ences and workshops were organized under the name Evo* (www.evostar.org).