What is Science? A Guide for Those Who Love It, Hate It, or Fear It, provides the reader with ways science has been done through discovery, exploration, experimentation and other reason-based approaches. It discusses the basic and applied sciences, the reasons why some people hate science, especially its rejection of the supernatural, and others who fear it for human applications leading to environmental degradation, climate change, nuclear war, and other outcomes of sciences applied to society.The author uses anecdotes from interviews and associations with many scientists he has encountered in his career to illustrate these features of science and their personalities and habits of thinking or work. He also explores the culture wars of science and the humanities, values involved in doing science and applying science, the need for preventing unexpected outcomes of applied science, and the ways our world view changes through the insights of science. This book will provide teachers lots of material for discussion about science and its significance in our lives. It will also be helpful for those starting out their interest in science to know the worst and best features of science as they develop their careers.

What is Science? A Guide for Those Who Love It, Hate It, or Fear It, provides the reader with ways science has been done through discovery, exploration, experimentation and other reason-based approaches. It discusses the basic and applied sciences, the reasons why some people hate science, especially its rejection of the supernatural, and others who fear it for human applications leading to environmental degradation, climate change, nuclear war, and other outcomes of sciences applied to society.The author uses anecdotes from interviews and associations with many scientists he has encountered in his career to illustrate these features of science and their personalities and habits of thinking or work. He also explores the culture wars of science and the humanities, values involved in doing science and applying science, the need for preventing unexpected outcomes of applied science, and the ways our world view changes through the insights of science. This book will provide teachers lots of material for discussion about science and its significance in our lives. It will also be helpful for those starting out their interest in science to know the worst and best features of science as they develop their careers.

This is a handbook that shows the reader how to construct an intellectual pedigree. It is also a history of science monograph because the completed intellectual pedigrees can be used individually or collectively to trace the influences of mentoring in the life sciences. The author uses Hermann Joseph Muller (1890-1967) (which includes his own intellectual pedigree) to show how knowledge was shifted from Italy to Germany and England, to France, and then to the American Colonies. Through Muller, the author goes in two directions, one leading to Huxley, Darwin, and Newton. The second leads to Agassiz, Malpighi, Borelli, and Galileo. The author also shows, from comparing 60 additional intellectual pedigrees, that about one third go to Newton, one third to Galileo and the rest to other icons of the past (e.g., Linnaeus, Lavoisier, Gay-Loussac, Leibniz). It shows how small was the pool of available scientists in the universities before the mid-19th century.This book will stimulate graduate students and faculty to construct their own intellectual pedigrees. It will also be of interest to historians and philosophers of science. The book discusses the role of mentoring, dividing this into inputs of intellectual development as well as outputs of development, using timelines arranged as circles. For each mentor, a brief account is given of that person's work and relation to the subject of the pedigree.

Few of us know much about the biology of sex determination, but what could be more interesting than to discover how we are shaped into males and females? In this book, Elof Carlson tells the incredible story of the difficult quest to understand how the body forms girls and boys. Carlson s history takes us from antiquity to the present day to detail how each component of human reproduction and sexuality was identified and studied, how this knowledge enlarged our understanding of sex determination, and how it was employed to interpret such little understood aspects of human biology as the origin of intersex births."

Traditional views of human nature focus on the supernatural, defining us as creatures with souls, minds, and spirits that transcend our physical attributes. In this provocative book, distinguished scientist and historian Elof Axel Carlson argues for a different understanding of ourselves based on our biology - cellular organization, genetics, life cycle, evolution, and our origins as a species. This interpretation would not negate our capacity for imagination, spiritual and emotional yearnings, or aesthetic appreciation for art, music, and literature. Carlson challenges educators, the media, and public policy makers to integrate the evidence from science more fully into our understanding of ourselves.

In 1907, Indiana passed the world s first involuntary sterilization law based on the theory of eugenics. In time, more than 30 states and a dozen foreign countries followed suit. Although the Indiana statute was later declared unconstitutional, other laws restricting immigration and regulating marriage on "eugenic" grounds were still in effect in the U.S. as late as the 1970s. A Century of Eugenics in America assesses the history of eugenics in the United States and its status in the age of the Human Genome Project. The essays explore the early support of compulsory sterilization by doctors and legislators; the implementation of eugenic schemes in Indiana, Georgia, California, Minnesota, North Carolina, and Alabama; the legal and social challenges to sterilization; and the prospects for a eugenics movement basing its claims on modern genetic science."

This latest book by Elof Carlson (The Unfit) is a first history of classical genetics, the era in which the chromosome theory of heredity was proposed and developed. Highly illustrated and based heavily on early 20th century original sources, the book traces the roots of genetics in breeding analysis and studies of cytology, evolution, and reproductive biology that began in Europe but were synthesized in the United States through new Ph.D. programs and expanded academic funding. Carlson argues that, influenced largely by new technologies and instrumentation, the life sciences progressed though incremental change rather than paradigm shifts, and he describes how molecular biology emerged from the key ideas and model systems of classical genetics. Readable and original, this narrative will interest historians and science educators as well as today's practitioners of genetics.

Today, most scientists regard the term "mutation" as a description of a change in an individual gene, and more precisely as some minute alteration of the DNA of that gene, especially a nucleotide substitution. But the idea of mutation has changed considerably from the pre-Mendelian concepts of Darwin's generation, who viewed "fluctuating variations" as the raw material on which evolution acted, to today's up-to-the-minute genomic context of mutation. Mutation: The History of an Idea from Darwin to Genomics explores six generations of mutation research, providing the backgroundthe people and the ideasfor this biological journey.
After exploring Darwin's and Francis Galton's concepts of mutation, Carlson shows how the 1900 rediscovery of Gregor Mendel's experiments let to a discontinuous model of evolution by mutation and how cytological investigations led to the chromosome theory of heredity of classical genetics in which there was random mutation in genes. Carlson details how Mendelian and biometric approaches to heredity and evolution were closely tied and how induction of mutations by radiation and chemical mutagens led to biochemical investigations of gene action, shifting attention to the chemistry of the gene. The interpretation of the gene as DNA and the deciphering of the genetic code then gave rise to molecular interpretations of mutation, views that also impacted evolutionary biology, population genetics, commercial development of plants and animals, and human genetics.
This book shows how generational definitions or assessments of mutation have responded to the technologies added to science and the experiments that abounded with the inquiries of each successive generation. These observations are combined with an exploration of how the nonscientific public has shifted its understanding and concern about mutations over the past 150 or more years. Carlson's historical approach in this bookexamining the evolution of a conceptreveals the way science works, incrementally by small steps of additions and replacements rather than by dramatic, and rare, paradigm shifts.

The Unfit, by Elof Carlson, explores the sources of a movement - negative eugenics - that was used to justify the Holocaust, which claimed millions of innocent lives in World War II. The title reflects the nearly three centuries of belief that some people are socially unfit by virtue of a defective biology, and echoes an earlier theory of degeneracy, dating to biblical antiquity, in which some people were deemed unfit because of some transgression against religious law. The author presents the first biological theory of degeneracy - onanism - and then follows the development of degeneracy theory throughout the nineteenth century and its application to a variety of social classes. The key intellectual theories and their proponents form the framework of this exploration, which includes the concepts of evolution and heredity and how they were applied to social problems. These ideas are followed into the twentieth century with the development of theories of positive and negative eugenics, the establishment of compulsory sterilization laws, racism and anti-Semitism, and the Holocaust. This story of misapplied science and technology is one that still haunts humanity in the twenty-first century. The ghost of eugenics recurs in many guises during debates and controversies about intelligence testing, genetic screening, prenatal diagnosis, gene therapy, new reproductive strategies, and uses of our genomic information. Carlson ends his discussion of the history of humanity in this arena with an exploration of the future of genetics that is based on new technologies and application of the Human Genome Project findings, as well as a discussion of the death of the old eugenics and of the problems that will not go away, including our ambivalence about our own biology.