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Leukemia continues to offer the scientist a unique opportunity to
gain new knowledge about the malignant transformation. As a result,
this multi-authored volume, devoted to advances which have occurred
over the last seven years, provides the reader with an important
new understanding of leukemia, but perhaps even more important,
predicts analogous, new developments in the other malignant
diagnoses. In this respect, this volume represents the cutting edge
of cancer research. This text is unique in that it includes in a
single volume the leading contributors to their respective fields
covering what the editors feel are the major advances in our
knowledge of the biology and therapy of leukemia over the last
seven years.
The European School of Oncology came into existence to respond to a
need for informa tion, education and training in the field of the
diagnosis and treatment of cancer. There are two main reasons why
such an initiative was considered necessary. Firstly, the teaching
of oncology requires a rigorously multidisciplinary approach which
is difficult for the Universi ties to put into practice since their
system is mainly disciplinary orientated. Secondly, the rate of
technological development that impinges on the diagnosis and
treatment of cancer has been so rapid that it is not an easy task
for medical faculties to adapt their curricula flexibly. With its
residential courses for organ pathologies and the seminars on new
techniques (laser, monoclonal antibodies, imaging techniques etc.)
or on the principal therapeutic controversies (conservative or
mutilating surgery, primary or adjuvant chemotherapy, radiotherapy
alone or integrated), it is the ambition of the European School of
Oncology to fill a cultural and scientific gap and, thereby, create
a bridge between the University and Industry and between these two
and daily medical practice.
Leukemia is a malignant disease which continues to play a cutting
edge role in the discovery of new basic knowledge about the
malignant process and about the potential for controlling these
malignant diseases. Molecular Genetics and Therapy of Leukemia
presents contributions by leading investigators and scientific
contributors to such topics as chromosome 16, chromosome 5, the
BCL-2 gene, 11q23 breakpoint leukemias, the p-53 suppressor gene
and oncogene, hematopoietic stem cells, cytokines, detection of
minimal residual disease in acute lymphoblastic leukemia,
autologous marrow transplantation, the retinoblastoma gene,
allogeneic bone marrow transplant and chemotherapy of acute
lymphoblastic leukemia.
Leukemia continues to offer the scientist a unique opportunity to
gain new knowledge about the malignant transformation. As a result,
this multi-authored volume, devoted to advances which have occurred
over the last seven years, provides the reader with an important
new understanding of leukemia, but perhaps even more important,
predicts analogous, new developments in the other malignant
diagnoses. In this respect, this volume represents the cutting edge
of cancer research. This text is unique in that it includes in a
single volume the leading contributors to their respective fields
covering what the editors feel are the major advances in our
knowledge of the biology and therapy of leukemia over the last
seven years.
Leukemia is a malignant disease which continues to play a cutting
edge role in the discovery of new basic knowledge about the
malignant process and about the potential for controlling these
malignant diseases. Molecular Genetics and Therapy of Leukemia
presents contributions by leading investigators and scientific
contributors to such topics as chromosome 16, chromosome 5, the
BCL-2 gene, 11q23 breakpoint leukemias, the p-53 suppressor gene
and oncogene, hematopoietic stem cells, cytokines, detection of
minimal residual disease in acute lymphoblastic leukemia,
autologous marrow transplantation, the retinoblastoma gene,
allogeneic bone marrow transplant and chemotherapy of acute
lymphoblastic leukemia.
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