This book constitutes the refereed proceedings of the 5th International Conference on Frontiers in Cyber Security, FCS 2022, held in Kumasi, Ghana, during December 13-15, 2022. The 26 full papers were included in this book were carefully reviewed and selected from 65 submissions. They were organized in topical sections as follows: ioT Security; artificial intelligence and cyber security; blockchain technology and application; cryptography; database security; quantum cryptography; and network security.