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Polycyclic hydrocarbons are of interest in many fields of science:
theoretical chemistry, physical chemistry, organic chemistry,
dyestuff chemistry and biology. With regard to the latter, I am
indebted to Dr. Regina Schoental of the Medical Research Council
for the review in this present work of carcinogenesis by polycyclic
hydrocarbons. This book is designed to present the facts in a
simple and clear order and to derive empirical rules from them, but
it does not present a com prehensive theory about polycyclic
hydrocarbons. An attempt is made instead to extend classical
symbolism into modern structural chemistry. Thus extensive use is
made of Robinson's aromatic sextet, which is applied in an
uncompromising and strict way. This quasi-classical attempt is
encouraged further by such completely unexpected dis coveries as
those of Dewar benzene and of the electronic asymmetry of formally
symmetric hydrocarbons. How difficult it is to break away from any
established way of thinking has been admirably expressed by Kekule
("Organische Chemie," 1861, Part 1, page 4, translated from the
German): "All our ideas are based, to an extent much greater than
we ordinarily believe, on those of our predecessors. Our
accumulated experience, the notions of which our training has
accustomed us to, of whatever kind they have been, influence the
course of our thoughts far more than we are willing to admit; only
too frequently the following of our regularly used, well trodden
way of thinking leads us to overlook the simplest of correlations."
Polycyclic hydrocarbons are of interest in many fields of science:
theoretical chemistry, physical chemistry, organic chemistry,
dyestuff chemistry and biology. With regards to the latter, I am
indebted to Dr. Regina Schoental of the Medical Research Council
for the review in this present work of carcinogenesis by polycyclic
hydrocarbons. This book is designed to present the facts in a
simple and clear order and to derive empirical rules from them, but
it does not present a com prehensive theory about polycyclic
hydrocarbons. An attempt is made instead to extend classical
symbolism into modern structural chemistry. Thus extensive use is
made of Robinson's aromatic sextet, which is applied in an
uncompromising and strict way. This quasi-classical attempt is
encouraged further by such completely unexpected dis coveries as
those of Dewar benzene and of the electronic asymmetry of formally
symmetric hydrocarbons. How difficult it is to break away from any
established way of thinking has been admirably expressed by Kekule
("Organische Chemie," 1861, Part 1, page 4, translated from
German): "All our ideas are based, to an extent much greater than
we ordinarily believe, on those of our predecessors. Our
accumulated experience, the notions of which our training has
accustomed us to, of whatever kind they have been, influence the
course of our thoughts far more than we are willing to admit; only
too frequently the following of our regularly used, well trodden
way of thinking leads to us overlook the simplest of correlations."
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