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This volume describes up-to-date techniques used in understanding
the molecular biology of acute myeloid leukemia (AML) and
addressing advances in diagnosis, classification, prognostication,
and therapeutic strategies to potentially impact overall patient
survival. The chapters in this book cover topics such as:
cytochemical staining, single-cell mass cytometry of AML and
Leukemia stem/progenitor cells, microsphere-based assessment of DNA
methylation for AML prognosis, a zebrafish model for evaluating the
function of human leukemic gene IDH1 and its mutation, and the
isolation of biologically active exosomes from plasma of patients
with cancer. Written in the highly successful Methods in Molecular
Biology series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting and avoiding known pitfalls. Cutting-edge and
practical, Acute Myeloid Leukemia: Methods and Protocols is a
valuable resource for scientists and researchers to further their
studies and advancements in the field of AML.
This volume describes up-to-date techniques used in understanding
the molecular biology of acute myeloid leukemia (AML) and
addressing advances in diagnosis, classification, prognostication,
and therapeutic strategies to potentially impact overall patient
survival. The chapters in this book cover topics such as:
cytochemical staining, single-cell mass cytometry of AML and
Leukemia stem/progenitor cells, microsphere-based assessment of DNA
methylation for AML prognosis, a zebrafish model for evaluating the
function of human leukemic gene IDH1 and its mutation, and the
isolation of biologically active exosomes from plasma of patients
with cancer. Written in the highly successful Methods in Molecular
Biology series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting and avoiding known pitfalls. Cutting-edge and
practical, Acute Myeloid Leukemia: Methods and Protocols is a
valuable resource for scientists and researchers to further their
studies and advancements in the field of AML.
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