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In the rapidly developing area of neuroimmunology, primary at-
tention has been given thus far to the bidirectional exchange of
information between the immune system and the neuroendocrine
system. Several recent texts on this subject are based alm ost
exclu- sively on experimental and clinical data obtained in
mammalian species. One of the interesting insights gained from
these studies is that the chemical messenger substances used in
this exchange by either system are the same, or at least closely
related to each other. Cytokines, primarily thought of as being
dispatched by cells of the immune system, have recently been
identified to be products of neural, in particular, glial elements.
Conversely, neuropeptides for- merly considered to be
characteristic of the neuroendocrine apparatus are now known to be
manufactured and dispatched by immuno- regulatory cells as weIl.
The present text is the first to provide an overview of the rich
body of information obtained in aseries of broadly based
comparative studies. This work in representatives of higher
invertebrates has opened new vistas, in particular, regarding the
immunomodulatory role played by opioid and other neuropeptides as
signal molecules in the ceIl-mediated internal regulation of the
immune system.
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The Ancients (Paperback)
Eric M. Smith; Nick Marsh
bundle available
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R305
Discovery Miles 3 050
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Ships in 10 - 15 working days
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