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Lipids in Plants and Algae: From Fundamental Science to Industrial
Applications, Volume 101 provides in-depth reviews on the most
important aspects of the field. Topics in this volume encompass the
most recent data about the physical properties of membrane lipids,
lipid biosynthesis and metabolism (including glycerolipids, fatty
acids, sterols, N-acylethanolamines, prostaglandins,
phytoprostane), lipid storage, acyl flux, the dynamic and transport
of glycerolipids, and the conversion of fatty acids into
hydrocarbons. Lipid metabolism and lipidomics in plants and algae
are one of the most challenging areas in biology, not only for
fundamental research but also for the sustainable production of
valuable molecules for green chemistry, including biofuel and
health.
This volume explores plastid evolution, structure, and function in
algae, plants and protists. The methods described in this book help
scientists visualize, fractionate, purify, and study primary and
secondary plastids in plant and algal materials. The chapters in
this book also look at various techniques to analyze plastids
through means of combining biology strategies from genetics,
genomics, proteomics, and lipidomics. Written in the highly
successful Methods in Molecular Biology series format, chapters
include introductions to their respective topics, lists of the
necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and tips on troubleshooting and
avoiding known pitfalls. Cutting-edge and thorough, Plastids:
Methods and Protocols is a valuable resource for students,
engineers, and researchers who are interested in this evolving
organelle and overall field.
Biological and chemical sciences have undergone an unprecedented
transformation, reflected by the huge use of parallel and automated
technologies in key fields such as genome sequencing, DNA chips,
nanoscale functional biology or combinatorial chemistry. It is now
possible to generate and store from tens of thousands to millions
of new small molecules, based on enhanced chemical synthesis
strategies. Automated screening of small molecules is one of the
technologies that has revolutionized biology, first developed for
the pharmaceutical industry and recently introduced in academic
laboratories. High-throughput and high-content screening allow the
identification of bioactive compounds in collections of molecules
(chemical libraries), being effective on biological targets defined
at various organisational scales, from proteins to cells to
complete organisms. These bioactive molecules can be therapeutic
drug candidates, molecules for biotech, diagnostic or agronomic
applications, or tools for basic research. Handling a large number
of biological (genomic and post-genomic), chemical and experimental
information, screening approaches cannot be envisaged without any
electronic storage and mathematical treatment of the data.
"Chemogenomics and Chemical Genetics" is an introductory manual
presenting methods and concepts making up the basis for this recent
discipline. This book is dedicated to biologists, chemists and
computer scientist beginners. It is organized in brief, illustrated
chapters with practical examples. Clear definitions of biological,
chemical and IT concepts are given in a glossary section to help
readers who are not familiar with one of these disciplines.
"Chemogenomics and Chemical Genetics" should therefore be helpful
for students (from Bachelor's degree level), technological platform
engineers, and researchers in biology, chemistry, bioinformatics,
cheminformatics, both in biotech and academic laboratories.
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