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In this superb topology text, the readers not only learn about knot theory, 3-dimensional manifolds, and the topology of embedded graphs, but also their role in understanding molecular structures. Most results described in the text are motivated by the questions of chemists or molecular biologists, though they often go beyond answering the original question asked. No specific mathematical or chemical prerequisites are required. The text is enhanced by nearly 200 illustrations and 100 exercises. With this fascinating book, undergraduate mathematics students escape the world of pure abstract theory and enter that of real molecules, while chemists and biologists find simple and clear but rigorous definitions of mathematical concepts they handle intuitively in their work.
This book contains the proceedings of the AMS Special Session on
Topology of Biopolymers, held from April 21-22, 2018, at
Northeastern University, Boston, MA. The papers cover recent
results on the topology and geometry of DNA and protein knotting
using techniques from knot theory, spatial graph theory,
differential geometry, molecular simulations, and laboratory
experimentation. They include current work on the following topics:
the density and supercoiling of DNA minicircles; the dependence of
DNA geometry on its amino acid sequence; random models of DNA
knotting; topological models of DNA replication and recombination;
theories of how and why proteins knot; topological and geometric
approaches to identifying entanglements in proteins; and
topological and geometric techniques to predict protein folding
rates. All of the articles are written as surveys intended for a
broad interdisciplinary audience with a minimum of prerequisites.
In addition to being a useful reference for experts, this book also
provides an excellent introduction to the fast-moving field of
topology and geometry of biopolymers.
In this superb topology text, the readers not only learn about knot theory, 3-dimensional manifolds, and the topology of embedded graphs, but also their role in understanding molecular structures. Most results described in the text are motivated by the questions of chemists or molecular biologists, though they often go beyond answering the original question asked. No specific mathematical or chemical prerequisites are required. The text is enhanced by nearly 200 illustrations and 100 exercises. With this fascinating book, undergraduate mathematics students escape the world of pure abstract theory and enter that of real molecules, while chemists and biologists find simple and clear but rigorous definitions of mathematical concepts they handle intuitively in their work.
This book is an elementary introduction to geometric topology and
its applications to chemistry, molecular biology, and cosmology. It
does not assume any mathematical or scientific background,
sophistication, or even motivation to study mathematics. It is
meant to be fun and engaging while drawing students in to learn
about fundamental topological and geometric ideas. Though the book
can be read and enjoyed by nonmathematicians, college students, or
even eager high school students, it is intended to be used as an
undergraduate textbook. The book is divided into three parts
corresponding to the three areas referred to in the title. Part 1
develops techniques that enable two- and three-dimensional
creatures to visualize possible shapes for their universe and to
use topological and geometric properties to distinguish one such
space from another. Part 2 is an introduction to knot theory with
an emphasis on invariants. Part 3 presents applications of topology
and geometry to molecular symmetries, DNA, and proteins. Each
chapter ends with exercises that allow for better understanding of
the material. The style of the book is informal and lively. Though
all of the definitions and theorems are explicitly stated, they are
given in an intuitive rather than a rigorous form, with several
hundreds of figures illustrating the exposition. This allows
students to develop intuition about topology and geometry without
getting bogged down in technical details.
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