In recent years the concept of the resource "nexus" has been both hotly debated and widely adopted in research and policy circles. It is a powerful new way to understand and better govern the myriad complex relationships between multiple resources, actors and their security concerns. Particular attention has been paid to water, energy and food interactions, but land and materials emerge as critical too. This comprehensive handbook presents a detailed review of current knowledge about resource nexus-related frameworks, methods and governance, including a broad set of inter-disciplinary perspectives. Written by an international group of scholars and practitioners, the volume focuses on rigorous research, including tools, methods and modelling approaches to analyse resource use patterns across societies and scales from a "nexus perspective". It also provides numerous examples from political economy to demonstrate how resource nexus frameworks can illuminate issues such as land grabs, mining, renewable energy and the growing importance of economies such as China, as well as to propose lessons and outlooks for sound governance. The volume seeks to serve as an essential reference text, source book and state-of-the-art, science-based assessment of this increasingly important topic - the resource nexus - and its utility in efforts to enhance sustainability of many kinds and implement the United Nations Sustainable Development Goals in an era of environmental and geopolitical change.