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In this volume the authors promote, endorse and stimulate research
in the vibrant field of biological inorganic chemistry. They
provide an overview of metallodrugs which have been rationally
designed to target specific biomolecules in the human body with a
view to generating targeted drugs or prodrugs with widespread
biomedical applications. The volume focuses on recent trends and
advances in relation to targeted metallodrugs as anti-cancer,
anti-microbial and anti-viral agents with an emphasis on their
design, development and mode of action. It also include recent
advances in the use of nanoparticles and nanoclusters as important
chaperones to deliver metallodrugs to their sites of action.
Volume 17, entitled Lead: Its Effects on Environment and Health of
the series Metal Ions in Life Sciences centers on the
interrelations between biosystems and lead. The book provides an
up-to-date review of the bioinorganic chemistry of this metal and
its ions; it covers the biogeochemistry of lead, its use (not only
as gasoline additive) and anthropogenic release into the
environment, its cycling and speciation in the atmosphere, in
waters, soils, and sediments, and also in mammalian organs. The
analytical tools to determine and to quantify this toxic element in
blood, saliva, urine, hair, etc. are described. The properties of
lead(II) complexes formed with amino acids, peptides, proteins
(including metallothioneins), nucleobases, nucleotides, nucleic
acids, and other ligands of biological relevance are summarized for
the solid state and for aqueous solutions as well. All this is
important for obtaining a coherent picture on the properties of
lead, its effects on plants and toxic actions on mammalian organs.
This and more is treated in an authoritative and timely manner in
the 16 stimulating chapters of Volume 17, which are written by 36
internationally recognized experts from 13 nations. The impact of
this recently again vibrant research area is manifested in nearly
2000 references, over 50 tables and more than 100 illustrations
(half in color). Lead: Its Effects on Environment and Health is an
essential resource for scientists working in the wide range from
material sciences, inorganic biochemistry all the way through to
medicine including the clinic ... not forgetting that it also
provides excellent information for teaching.
In an ever-increasing domain of activity, Amino Acids, Peptides and
Proteins provides an annual compilation of the world's research
effort into this important area of biological chemistry. Comprising
a comprehensive review of significant developments at this
biology/chemistry interface, each volume opens with an overview of
amino acids and their applications. Work on peptides is reviewed
over several chapters, ranging from current trends in their
synthesis and conformational and structural analysis, to
peptidomimetics and the discovery of peptide-related molecules in
nature. The application of advanced techniques in structural
elucidation is incorporated into all chapters, whilst periodic
chapters on metal complexes of amino acids, peptides and
beta-lactams extend the scope of coverage. Efficient searching of
specialist topics is facilitated by the sub-division of chapters
into discrete subject areas, allowing annual trends to be
monitored. All researchers in the pharmaceutical and allied
industries, and at the biology/chemistry interface in academia will
find this an indispensable reference source. Volume 36 covers
literature published during 2003.
Amino Acids, Peptides and Proteins comprises a comprehensive review
of significant developments at this biology/chemistry interface.
Each volume of this Specialist Periodical Report opens with an
overview of amino acids and their applications. Work on peptides is
reviewed over several chapters, ranging from current trends in
their synthesis and conformational and structural analysis, to
peptidomimetics and the discovery of peptide-related molecules in
nature. The application of advanced techniques in structural
elucidation is incorporated into all chapters, whilst periodic
chapters on metal complexes of amino acids, peptides and
beta-lactams extend the scope of coverage. Efficient searching of
specialist topics is facilitated by the sub-division of chapters
into discrete subject areas, allowing annual trends to be
monitored. Researchers in the pharmaceutical and allied industries,
and at the biology/chemistry interface in academia will find this
an indispensable reference source. Specialist Periodical Reports
provide systematic and detailed review coverage in major areas of
chemical research. Compiled by teams of leading experts in their
specialist fields, this series is designed to help the chemistry
community keep current with the latest developments in their field.
Each volume in the series is published either annually or
biennially and is a superb reference point for researchers.
www.rsc.org/spr
In an ever-increasing domain of activity Amino Acids Peptides and
Proteins provides an annual compilation of the world's research
effort into this important area of biological chemistry. Volume 33
provides a review of literature published during 2000. Comprising a
comprehensive review of significant developments at this
biology/chemistry interface each volume opens with an overview of
amino acids and their applications. Work on peptides is reviewed
over several chapters ranging from current trends in their
synthesis and conformational and structural analysis to
peptidomimetics and the discovery of peptide-related molecules in
nature. The application of advanced techniques in structural
elucidation is incorporated into all chapters whilst periodic
chapters on metal complexes of amino acids peptides and
beta-lactams extend the scope of coverage. Efficient searching of
specialist topics is facilitated by the sub-division of chapters
into discrete subject areas allowing annual trends to be monitored.
All researchers in the pharmaceutical and allied industries and at
the biology/chemistry interface in academia will find this an
indispensable reference source.
In an ever-increasing domain of activity Amino Acids Peptides and
Proteins provides an annual compilation of the world's research
effort into this important area of biological chemistry. Volume 31
provides a review of literature published during 1998. Comprising a
comprehensive review of significant developments at this
biology/chemistry interface each volume opens with an overview of
amino acids and their applications. Work on peptides is reviewed
over several chapters ranging from current trends in their
synthesis and conformational and structural analysis to
peptidomimetics and the discovery of peptide-related molecules in
nature. The application of advanced techniques in structural
elucidation is incorporated into all chapters whilst periodic
chapters on metal complexes of amino acids, peptides and
beta-lactams extend the scope of coverage. Efficient searching of
specialist topics is facilitated by the sub-division of chapters
into discrete subject areas allowing annual trends to be monitored.
All researchers in the pharmaceutical and allied industries and at
the biology/chemistry interface in academia will find this an
indispensable reference source.
In an ever-increasing domain of activity Amino Acids Peptides and
Proteins provides an annual compilation of the world's research
effort into this important area of biological chemistry. Volume 29
provides a review of literature published during 1996. Comprising a
comprehensive review of significant developments at this
biology/chemistry interface each volume opens with an overview of
amino acids and their applications. Work on peptides is reviewed
over several chapters ranging from current trends in their
synthesis and conformational and structural analysis to
peptidomimetics and the discovery of peptide-related molecules in
nature. The application of advanced techniques in structural
elucidation is incorporated into all chapters whilst periodic
chapters on metal complexes of amino acids, peptides and
beta-lactams extend the scope of coverage. Efficient searching of
specialist topics is facilitated by the sub-division of chapters
into discrete subject areas allowing annual trends to be monitored.
All researchers in the pharmaceutical and allied industries and at
the biology/chemistry interface in academia will find this an
indispensable reference source.
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