|
Showing 1 - 5 of
5 matches in All Departments
An explosion of information has occurred since scientists began to
define the molecular events that describe the malignant
transformation and progression of cells and their development
towards a life-threatening metastatic disease. The First
International Congress on Molecular Staging of Cancer, held in
Munich in December 2001, aimed to establish an international
platform of exchange among molecular biologists, cell biologists,
tumor immunologists, and clinical and surgical oncologists. This
network approach should be fruitful for both clinicians and
researchers. The highlighted topics included tumor-associated
proteolysis, minimal residual disease, new approaches for molecular
diagnosis and targeting, and the first molecular staging models.
One session focused on technology transfer, opening up a new field
of funding for innovative concepts. Finally, the impact of
molecular staging on clinical strategies was discussed.
Whenever the integrity of the skin is impaired, via trauma or
surgical incision, wounds und wound healing are the natural
consequences. Thus, every physician should be interested in the
biological processes involved in wound healing. The physician does
not usually interfere with these natural processes, knowing that
the body heals itself (natura sanat). It is not until the natural
wound healing process is disturbed, that we realize how little we
know about this area. Our limited knowledge is not even available
to most physicians. Advances in the areas of cell-and molecular
biology have also resulted in substantial progress in the field of
wound healing. Today, we know that the process of tissue repair
occurs in three phases and is controlled by specific cells. These
cells release potent mediators which in turn regulate the function
of other cells surrounding the area. "Certain rules apply to the
healing of wounds and injured tissue. You must follow nature for
nature will never follow you," this sentence writen by Paracelsus
in his book "Chirurgia magna" is still valid today. Current reseach
in wound healing is exploring these rules and integrating them into
new therapeutical concepts. The purpose of this book is to make
current knowledge on basic healing processes, research in this area
and on wound management available to most physicians. Due to the
importance of wound healing and the successful combination of basic
science and clinical aspects, I would like this book to be widely
accepted.
It is a great pleasure and honor to be asked to participate in the
translation of this important and historical volume on thoracic
surgery and to provide this foreword. Martin Kirschner of
Mannheim/Heidelberg was an early pioneer in thoracic and esophageal
surgery. His operation for bypass of the esophagus using the entire
stomach remains a standard of the surgical armamentarium to this
date. The original Kirschner Textbook of Surgery was a standard in
its day. We are fortunate that Professors H. Pichlmaier and F.W.
Schildberg and other colleagues have provided us with this
important modern successor of a classic textbook. The reader is
rewarded by an extensive treatise which includes not only the most
up to date techniques in pulmonary, esophageal, mediastinal, and
chest wall (including breast) surgery but also provides an
excellent perspective on the techniques used by pioneers in the
field. Although some of these early techniques are not commonly
used today, knowledge of their use and application broadens the
capability of the thoracic surgeon. Changing times bring renewed
problems with infectious diseases. Knowledge of the management of
the pleural space and pulmonary infectious problems is a critical
part of the education of the thoracic surgeon.
Die Neuauflage dieses Standardwerkes der 50er Jahre ist vollst{ndig
}berrarbeitet. Sie umfa t vom Stellenwert der pr{operativen
Kernspintomographie bis zu den Ergebnissen der klinischen
Lungentransplantation alle Aspekte der Thorax- chirurgie. Die
zahlreichen Abbildungen operativer Details werden neben Chirurgen
auch Pulmologen, Anaesthesiologen und Radiologen interessieren.
In kaum einem Bereich der Medizin sind experimentelle und klinische
Forschung so eng miteinander verknupft wie in der Chirurgie. Ange-
fangen von Untersuchungen zu verschiedenen Naht- und Anastomo-
senmethoden bis zu weitreichenden Verfahren der Herz-Lungen-
Maschinenanwendung, der Organkonservierung und schliesslich der
Organtransplantation sind die engen Verflechtungen von Experi- ment
und klinischer Anwendung offensichtlich. Immer wenn experi-
mentelle Grundlagen in die Klinik ubertragen werden, mussen exakte
UEberprufungen der erwarteten Ergebnisse mit ihren Auswir- kungen
auf den Kranken in ihr Recht treten. Wie weit hier retro- spektive
Untersuchungen ausreichen oder prospektiven Studien grundsatzlich
der Vorrang gebuhrt, ist immer wieder Gegenstand der Diskussion. In
einem ersten Teil werden diese und ahnliche Grundsatzfragen
chirurgischer Forschung von verschiedenen Standpunkten aus einge-
hend beleuchtet, gefolgt von speziellen Darstellungen exemplari-
schen Charakters aus fast allen Bereichen der Chirurgie. Dabei
konnte Vollstandigkeit nicht angestrebt werden. Die Vielfalt der
Aussagen lasst dennoch klare Konturen erkennen und gibt Richtun-
gen fur kunftige Forschungen an. Es liegt in der Natur der Sache,
dass die Verflechtungen mit vielen Nachbardisziplinen deutlich
werden. Georg Heberers besonderes Interesse galt stets der
Grundlagen- forschung in der Chirurgie sowie der Pathophysiologie
des opera- tiven Eingriffs und seiner Folgen. Es lag deshalb nahe,
ihm zu sei- nem 65. Geburtstag ein Symposium zum Thema "Stand und
Gegen- stand chirurgischer Forschung" zu widmen. Die dabei
gehaltenen Vortrage bilden den Kern des nun vorliegenden Buches
gleichen Titels. Mitaufgenommen wurden zahlreiche Einzelbeitrage
seiner Schuler und Freunde aus speziellen Gebieten, damit die
Breite chir- urgischer Forschung an einzelnen Beispielen sichtbar
wird.
|
You may like...
Morbius
Jared Leto, Matt Smith, …
DVD
R179
Discovery Miles 1 790
Loot
Nadine Gordimer
Paperback
(2)
R398
R330
Discovery Miles 3 300
|