This book constitutes the thoroughly refereed and revised selected papers from the 22nd International Workshop on Multi-Agent-Based Simulation, MABS 2022, which took place virtually during May 8-9, 2022. The conference was originally planned to take place in Auckland, New Zealand, but had to change to an online format due to the COVID-19 pandemic. The 11 papers included in these proceedings were carefully reviewed and selected from 17 submissions. They focus on finding efficient solutions to model complex social systems, in areas such as economics, management, organisational and social sciences in general.

Fabian Lorig develops a procedure model for hypothesis-driven simulation studies which supports the design, conducting, and analysis of simulation experiments. It is aimed at facilitating the execution of simulation studies with regard to the replicability and reproducibility of the results. In comparison to existing models, this approach is based on a formally specified hypothesis. Each step of the simulation study can be adapted to the central hypothesis and performed in such a way that it can optimally contribute to the verification and thus to the confirmation or rejection of the hypothesis.