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Covering all aspects of neuropathology, this updated volume in the
Diagnostic Pathology series is an excellent point-of-care resource
for pathologists at all levels of experience and training-both as a
quick reference and as an efficient review to improve knowledge and
skills. The third edition is an easy-to-use, one-stop reference for
the most recent clinical, pathological, histological, and molecular
knowledge in the field. It offers complete information on lesions
of the brain, sellar region, and peripheral nerves, as well as
benign cysts and selected infectious, inflammatory, reactive,
vascular, and cortical dysplastic lesions, enabling you to arrive
at the correct diagnosis and prepare actionable, useful reports.
Incorporates new WHO Classification of Tumors of the Central
Nervous System, 5th Edition Offers information on neoplasms of the
brain, sellar region, and peripheral nerves, as well as benign
cysts and selected infectious, inflammatory, reactive, and vascular
lesions, aiding you in arriving at the correct diagnosis Emphasizes
surgical pathology but also provides significant content on
nonneoplastic diseases that present with focal lesions, especially
those that are potentially misinterpreted as neoplasms Features new
and updated chapters detailing several types of tumors that have
been reclassified due to recent molecular driver information,
cIMPACT-NOW recommendations, and the WHO Classification, 5th
Edition Features nearly 1,700 annotated images throughout,
including neuroimaging studies, histology and immunohistochemical
stains, and high-quality medical illustrations Incorporates
time-saving features such as a templated, highly formatted design;
concise, bulleted text; a variety of test data tables; key facts in
each chapter; and an extensive index Includes the enhanced eBook
version, which allows you to access all text, figures, and
references on a variety of devices
This book is a rich source of information on biomarkers applicable
to the pathology of neoplastic disorders of the brain. Thorough
descriptions are provided of the techniques currently available for
clinical and experimental evaluation of biomarkers in brain
neoplasms, including in situ hybridization, array-based methods,
methylation profiling, next-generation sequencing, and practical
gene panels. Incorporation of multiple biomarkers in the
development of molecular subgroups with biologic and therapeutic
relevance is also discussed. A section on biobanking covers the
equally important topic of optimal preservation of tissue and
includes consideration of ethical considerations raised by the use
of tissue obtained in clinical settings. The closing section
discusses the major categories of neoplastic disorders involving
the nervous system, with emphasis on diagnostic, prognostic, and
predictive biomarkers used in the pathologic evaluation of
different types of brain tumor.
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