The rationale for using intraoperative irradiation (IORT) is based on the realization that tolerable doses of external beam radiation are often insufficient to achieve control of locally advanced malignancies. In these instances, the IORT component of treatment becomes the optimal conformal technique of irradiation, since dose-limiting organs or structures can either be surgically displaced or protected by placement of lead shielding. This fully revised and expanded second edition is of interest to those with intraoperative electron (IOERT) capabilities, high-does-rate brachytherapy (HDR-IORT) capabilities, or both. Techniques, indications, and results are discussed by disease site. Each chapter is dual authored by a radiation oncologist and a surgeon, giving a balanced presentation of clinical scenarios. Issues of basic science and physics are also covered, and a notable chapter on normal tissue tolerance is included. Intraoperative Irradiation: Techniques and Results, Second Edition is a superb compilation, providing essential cutting-edge knowledge. It is a foundation for physicians as IORT develops and becomes more widely available.

The rationale for using intraoperative irradiation (IORT) is based on the realization that tolerable doses of eternal beam radiation are often insufficient to achieve control of locally advanced malignancies. In these instances, the IORT component of treatment becomes the optimal conformal technique of irradiation, since dose-limiting organs or structures can either be surgically displaced or protected by placement of lead shielding. This fully revised and expanded second edition is of interest to those with intraoperative electron (IOERT) capabilities, high-dose-rate brachytherapy (HDR-IORT) capabilities, or both. Techniques, indications, and results are discussed by disease site. Each chapter is dual authored by a radiation oncologist and a surgeon, giving a balanced presentation of clinical scenarios. Issues of basic science and physics are also covered, and a notable chapter on normal tissue tolerance is included. Intraoperative Irradiation: Techniques and Results, Second Edition is a superb compilation, providing essential cutting-edge knowledge. It is a foundation for physicians as IORT develops and becomes more widely available.

Intraoperative electron radiation therapy (IOERT) is an advanced technique that permits the precise delivery of radiotherapy for the treatment of cancer. IOERT complements the surgical procedure by providing an additional biological treatment margin, and can be used in the treatment of unresected cancer, residual neoplastic disease or tumor bed areas at high risk of recurrence. This atlas comprehensively documents the techniques involved in IOERT and the positive long-term results that can be achieved in patients with a variety of tumors, including head and neck, gastrointestinal and gynecological cancers, pediatric cancers, and sarcomas. The didactic, case solution approach, supplemented by many detailed and informative illustrations, serves to demonstrate the high value of IOERT in different contexts. This book will be invaluable to all specialists in cancer treatment, including surgeons.